Calibration of Dynamic Molecular Rulers Based on Plasmon Coupling between Gold Nanoparticles, Nano Letters. 5, 2246

Physics Department, Biophysics Graduate Program, and Chemistry Department, University of California, Berkeley, California 94720, USA.
Nano Letters (Impact Factor: 13.59). 12/2005; 5(11):2246-52. DOI: 10.1021/nl051592s
Source: PubMed


Pairs of noble metal nanoparticles can be used to measure distances via the distance dependence of their plasmon coupling. These "plasmon rulers" offer exceptional photostability and brightness; however, the advantages and limitations of this approach remain to be explored. Here we report detailed plasmon peak versus separation calibration curves for 42- and 87-nm-diameter particle pairs, determine their measurement errors, and describe experimental procedures to improve their performance in biology, nanotechnology, and materials sciences.

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    • "Moreover, the coupling between two nanoparticles in close proximity produces an alteration of the plasmon spectra. This alteration has been used as a nanometric ruler to determine the distance between them [19] [20]. In a previous work, [4] we theoretically showed that the coupling between two nanoparticles is highly sensitive to the polarization of the external field. "
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