Gender differences in polysomnographic sleep in young healthy sleepers
ABSTRACT Middle-aged and elderly populations exhibit gender differences in polysomnographic (PSG) sleep; however, whether young men and women also show such differences remains unclear. Thirty-one young healthy sleepers (16 men and 15 women, aged 18 to 30 yr, mean+/-SD, 20.5+/-2.4 yr) completed 3 consecutive overnight sessions in a sleep laboratory, after maintaining a stable sleep-wake cycle for 1 wk before study entry. Standard PSG sleep and self-rated sleepiness data were collected each night. Across nights, women showed better sleep quality than men: they fell asleep faster (shorter sleep onset latency) and had better sleep efficiency, with more time asleep and less time awake (all differences showed large effect sizes, d=0.98 to 1.12). By contrast, men were sleepier than women across nights. Both men and women demonstrated poorer overall sleep quality on the first night compared with the subsequent 2 nights of study. We conclude young adult healthy sleepers show robust gender differences in PSG sleep, like older populations, with better sleep quality in women than in men. These results highlight the importance of gender in sleep and circadian rhythm research studies employing young subjects and have broader implications for women's health issues relating to these topics.
- SourceAvailable from: Michelle A MillerSleep Disorders, 03/2012; , ISBN: 978-953-51-0293-9
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ABSTRACT: Insomnia affects midlife women as they approach and experience menopause at a rate higher than most other stages of life. Insomnia is considered one of the climacteric symptoms of menopause, which can be controlled with hormone replacement therapy (HRT). This study examined the relationship between menopause and sleep in women with insomnia and compared the sleep quality of menopausal women with and without HRT. A total of 74 women (age range=40-59 years old) with insomnia who were either pre or peri/post menopause were evaluated at Laval University's Sleep Disorders Center as part of ongoing clinical trials of insomnia therapies. All participants completed daily sleep diaries for a 2-week period and a series of psychological and insomnia questionnaires, followed by three consecutive nights of polysomnographic evaluation (PSG). A detailed medical history interview was taken by the study physician. PSG measures showed that menopausal women had significantly longer total wake time (TWT, 84.2 vs. 63.2 min, Cohen's d=0.504) and lower sleep efficiency (SE, 81.8% vs. 86.0%, d=0.487) than the non-menopausal women. Women using HRT did not show significantly better sleep compared to those who did not use HRT. No significant difference was observed between menopausal groups on subjectively assessed sleep parameters. Menopause may contribute to specific aspects of sleep disturbances in midlife women with insomnia. Use of HRT for menopausal symptoms does not seem to attenuate such disturbances, although further investigation using hormonal level dosing and a larger sample size is warranted.Sleep Medicine 01/2011; 12(1):65-9. DOI:10.1016/j.sleep.2010.09.003 · 3.10 Impact Factor
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ABSTRACT: To describe the effect of nursing caregiving on infant sleep-wake states by gender in preterm infants. Descriptive measures at 34 weeks postmenstrual age and at discharge. Twenty-two hospitalized preterm infants. Infant state and caregiving episodes were coded in 15-second intervals from video recordings of approximately three hours duration. Time plots of state and caregiving were analyzed visually to summarize spontaneous state changes and state change associated with caregiving. Sleep and wake state distribution did not differ statistically by gender; however, the rate of state change in male infants was twice that of females (p=.012) at discharge. At discharge, male infants received approximately twice as many care episodes as females. At discharge, the rate of state change in response to caregiving in male infants was four times that of female infants (p=.026). Males exhibited a greater percentage of caregiving episodes related to state change than did females at discharge (p=.018). Findings suggest further exploration of possible gender differences in state regulation and state change in response to caregiving.Neonatal network: NN 01/2008; 27(1):15-22. DOI:10.1891/0730-08188.8.131.52