Two cases of maxillary cancer with a similar clinical course and imaging findings but markedly different levels of FDG uptake

Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Clinical Nuclear Medicine (Impact Factor: 3.93). 01/2006; 30(12):810-2. DOI: 10.1097/01.rlu.0000187611.64235.61
Source: PubMed


We report two cases of poorly differentiated squamous cell carcinoma of the left maxillary sinus. Both patients had a similar clinical course and similar imaging findings. However, FDG uptake by the 2 lesions was very different. The SUVs of the tumor lesions of patient I and 2 were 20.67 and 7.56, respectively. Histopathologically, hematoxylin and eosin (H&E) stained sections (X200) were packed with tumor cells, with many more inflammatory cells seen in patient 1. When dealing with cases of carcinoma of the head neck region where tumors are often accompanied by inflammation, we should bear in mind that FDG uptake by tumors is strongly influenced by the activity and timing of inflammation within the tumor lesions.

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