The effect of adding calcium lactate to xylitol chewing gum on Remineralization of enamel lesions
ABSTRACT The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs were used as controls and stored in a humidifier while half were mounted into oral appliances worn by 10 volunteers (22-27 years old, 2 males and 8 females) in a three-leg trial, during which they wore the appliance without chewing gum, chewed gum containing xylitol + calcium lactate or chewed gum containing only xylitol 4 times a day for 2 weeks. Calcium concentrations in the enamel surfaces of control and test slabs were measured by X-ray spectrometry and degrees of remineralization were calculated. The mean degree of remineralization was greater after chewing xylitol-Ca gum (0.46 +/- 0.10) than after no gum (0.16 +/- 0.14) or after chewing xylitol gum (0.33 +/- 0.10) (p < 0.01). In conclusion, chewing gum containing xylitol + calcium lactate could enhance remineralization of enamel surface compared to chewing gum containing only xylitol or no gum chewing.
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ABSTRACT: The aim of this study was to examine the effect of a fluoride and xylitol containing toothpaste on the remineralization of human enamel using Quantitative Light-induced Fluorescence (QLF). Human extracted teeth were cut longitudinally into three or four parts, and artificial subsurface lesion windows (2 mm x 3 mm) were created by immersion in demineralizing solution. Each enamel sample (n = 7) was treated for 3 min at 25 degrees C twice a day for consecutive 14 days with the slurry of a silica-based toothpaste 1) without F- and xylitol (blank), 2) with 500 ppm F- and 3) with 500 ppm F- and 5% xylitol toothpaste. In addition, we measured the remineralization ability of a commercially available toothpaste 4) with 500 ppm F-. The average fluorescence loss F (%) and lesion size (mm2) were determined with QLF. Another variable, delta Q, which was defined as the fluorescence loss integrated over the lesion size (%, mm2), was calculated. The results showed that the combination of 500 ppm F- and 5% xylitol toothpaste significantly (P < 0.05) recovered both the size and delta Q compared to the other groups. These findings suggested that inclusion of xylitol in fluoride toothpaste might be useful to enhance the remineralization in vivo.Journal of Oral Science 04/2007; 49(1):67-73. DOI:10.2334/josnusd.49.67 · 0.92 Impact Factor
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ABSTRACT: Objective: To analyze in vitro the demineralization pattern of bovine enamel as a function of pH and immersion time variations in a demineralizing solution used to simulate the natural caries process. Method: The sample consisted of 80 enamel blocks, randomly assigned to 4 groups (n=20): GA= pH 5.0 solution for 16 hours; GB= pH 5.0 solution for 32 hours; GC= pH 4.7 solution for 16 hours and GD= pH 4.7 solution for 32 hours. All specimens were stored at 37ºC during the whole experimental period. After exposure to the demineralizing solution, the specimens were prepared and evaluated under polarized light microscopy (PLM) and scanning electron microscopy (SEM). The data from SEM analysis were evaluated descriptively, while the results from PLM analysis were subjected to ANOVA and Tukey's tests, with a 95% significance level (p16 hours or lower pH of the solution were used.Pesquisa Brasileira em Odontopediatria e Clínica Integrada 01/2008; 8(2):233-238.