Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.
ABSTRACT CONTEXT: Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins. CASE REPORT: We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.
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ABSTRACT: Hidradenoma papilliferum is an uncommon, benign, cystic, papillary tumor that occurs almost exclusively in the female anogenital region. Bartholin's abscess is also an anogenital cystic lesion caused by obstruction of Bartholin's duct with an overlying infection. Concomitant presentation of Bartholin's abscess and Hidradenoma papilliferum is unique. A 43-year-old African American woman presented with a painful cystic mass on the left labia majora. A preoperative diagnosis of Bartholin's abscess was made. During excision and draining, an additional tan-brown dermal nodule was removed which demonstrated histological features of Hidradenoma papilliferum. We present what we believe to be the first case of Bartholin's abscess arising in hidradenoma papilliferum and its clinical significance.Cases Journal 02/2008; 1(1):282. DOI:10.1186/1757-1626-1-282
- Revista brasileira de malariologia e doenças tropicais. Publicações avulsas 02/1982; 34:1-31.
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ABSTRACT: We present the case of a 61-year-old woman who presented with a vulvar mass. Morphological and immunohistochemical analysis identified cellular angiofibroma. In this type of tumor, local recurrence is rare and metastasis has not bee described. Mesenchymal neoplasms of the vulva require surgical excision with free margins and accurate differential diagnosis.Clínica e Investigación en Ginecología y Obstetricia 04/2008; 35(2). DOI:10.1016/S0210-573X(08)73046-6