Hemangiopericytoma of the spleen: Unusual presentation as multiple abscess

1Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
World Journal of Surgical Oncology (Impact Factor: 1.2). 02/2005; 3:77. DOI: 10.1186/1477-7819-3-77
Source: PubMed

ABSTRACT Hemangiopericytoma is a soft tissue vascular neoplasm arising from capillary pericytes and is found throughout the body in soft tissues and bone. It was first described in 1942. Primary vascular neoplasm of the spleen constitutes the majority of nonhaematolymphoid splenic tumors like haemangioma, lymphangioma, hemangioendothelioma, hemangiopericytoma etc. Splenic hemangiopericytoma is a rare tumor and probably first case was described in 1989. Uptill now only eight cases are reported in the English literature.
A-35-year old male presented with fever and dull aching pain in left hypochondriac region. Radiological evaluation showed presence of multiple abscesses in spleen. Investigations were done to rule out common causes of abscess in spleen. After failure of medical management, he was subjected to elective splenectomy. There were dense adhesions between the spleen and the adjacent structures and the diaphragm. The histopathology of the resected specimen showed hemangiopericytoma of spleen.
The present case illustrate that the hemangiopericytoma of spleen can mimic as multiple abscess. Splenectomy is the treatment of choice.

Download full-text


Available from: Ajay K Khanna, Aug 09, 2015
  • Source
    • "Splenic hemangiopericytoma is also a very rare tumor and probably the first case was described in 1989 by Guadalajara et al., and so far, only 10 patients (9 adult, 1 child) consisting of 7 boys and 3 girls with a mean age of 38.3 years (range, 10 to 63 years) have been reported in the literature [5] [6] [7] [8] [9] [10] [11] [12] [13] "
    [Show abstract] [Hide abstract]
    ABSTRACT: Splenic hemangiopericytoma is a very rare tumor. So far only 10 patients (9 adults, 1 child) have been reported in the literature and all of them were treated with total splenectomy. Herein, we report the first infant case of the splenic hemangiopericytoma in a 10-month-old girl and the first case that was treated with partial splenectomy for splenic hemangiopericytoma.
    Fetal and pediatric pathology 03/2012; 31(4):248-53. DOI:10.3109/15513815.2012.656827 · 0.40 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Vascular benign lesions are the most common non-hematological splenic primary tumors. Although rare they may sometimes pose problems in differential diagnosis, because of their morphologic heterogeneity. We present vascular lesions of the spleen, which were found in archive of the Chair of Pathomorphology. Immunohistochemistry including CD34, CD31, factor VIII, CD8, CD21, CD68, lysosyme, GLUT-1, D2-40, VEGFR3, SMA, Ki67 were performed. 8 benign vascular lesions were identified, including two hamartomas, two lesions representing sclerosing angiomatoid nodular transformation (SANT) and four hemangiomas. We present briefly the spectrum of vascular lesions occurring in the spleen and discuss differential diagnosis and nosological status of selected lesions.
    Polish journal of pathology: official journal of the Polish Society of Pathologists 01/2008; 59(1):33-41. · 0.83 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Infantile myofibromatosis (IM) is a rare soft tissue tumor of infancy and childhood. We report the case of a newborn girl with an abdominal tumor discovered at 32 weeks of gestation by fetal ultrasound. She underwent a laparotomy for an unexplained abdominal mass 20 days after birth. The tumor originated from the spleen and was removed by splenectomy. There were no other abnormal findings on diagnostic modalities. Based on the histological examinations, the tumor was diagnosed as an IM. Although extremely rare during the neonatal period, solitary type IM should be considered as a differential diagnosis of the splenic tumor.
    Journal of Pediatric Surgery 02/2008; 43(1):227-30. DOI:10.1016/j.jpedsurg.2007.08.060 · 1.31 Impact Factor
Show more