[An outbreak of lymphogranuloma venereum in Western Europe].

Service de dermato-vénéréologie, pavilion Tarnier, hôpital Cochin, 75679 Paris.
La Revue du praticien 11/2005; 55(16):1747-50.
Source: PubMed


Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by Chlamydia trachomatis serotypes L1, L2, and L3. It is endemic in tropical areas, while seldom in industrialised countries. Since 2002, an outbreak of rectal LGV has been observed among men having sex with men, in Netherlands, France, and other countries of Western Europe. After an incubation period of 2 days to 2 months, LGV develops in three stages: ulcerated papule; inflammatory satellite lymph node and/or proctitis; chronic inflammatory complications (fistulas and sclerosis). Chlamydia trachomatis infection is confirmed by PCR and serovars is identified by RFLP of omp1 gene amplified by PCR. Recommended first line treatment is doxycycline for at least 21 days.

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    • "Serovars L1 to L3 can infect both urogenital and rectal tissues, causing lymphogranuloma venereum (LGV) (Bauwens et al., 2002). It has been recently reported that the LGV serovars can cause occasional outbreaks of LGV among men having sex with men in industrialized nations (Farhi & Dupin, 2005). Chlamydia pneumoniae is a major cause of various respiratory illnesses, and respiratory infection with C. pneumoniae is also linked to cardiovascular pathologies such as atherosclerosis (Campbell & Kuo, 2002, 2004). "
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