Article

Quantitative anatomical differences in central corneal thickness values determined with scanning-slit corneal topography and noncontact specular microscopy.

Department of Anatomy and Human Embryology, Faculty of Medicine, University of Valencia, Spain.
Cornea (impact factor: 1.73). 03/2006; 25(2):203-5. pp.203-5
Source: PubMed

ABSTRACT This study was designed to analyze the differences in central corneal thickness values determined with noncontact specular microscopy and scanning-slit corneal topography. The measurements were performed on the same eye.
We analyzed the central corneal thickness values of 93 patients (n = 93) by means of noncontact specular microscopy (Topcon SP-2000P noncontact specular microscope, Topcon Corp., Tokyo, Japan) and scanning-slit corneal topography (Orbscan Topography System II, Orbscan Inc., Salt Lake City, UT). One experienced physician performed 3 consecutive central corneal thickness measurements with both devices.
The central corneal thickness values obtained by means of Orbscan pachymetry were 17 +/- 2.7 (range, 12-24) microm greater. A significant correlation was observed between scanning-slit corneal topography and noncontact specular microscopy (Pearson correlation coefficient, r = 0.976; P < 0.001).
Researchers should know of the existence of this difference between noncontact specular microscopy and Orbscan pachymetry when interpreting central corneal thickness values.

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    Article: Central corneal thickness: z-ring corneal confocal microscopy versus ultrasound pachymetry.
    Erica Brugin, Alessandra Ghirlando, Catia Gambato, Edoardo Midena
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    ABSTRACT: To compare the repeatability and validity of corneal pachymetry by a corneal confocal microscope with a z-axis adapter (Confoscan 4.0 with z-ring adapter: z-CS4) versus ultrasound (US) pachymetry in the measurement of central corneal thickness (CCT). CCT in 44 eyes of 44 subjects was determined with z-CS4. Z-CS4 exams were used to estimate the repeatability of thickness measurement by z-ring adapter for this confocal microscope. Intraclass Correlation Coefficient (ICC) between two different z-CS4 users was also determined. CCT in the same 44 eyes was determined with US pachymetry and measurements were compared with z-CS4 CCT. Z-CS4 CCT showed high intrainstrument reproducibility (ICC = 0.989; 95%CI 0.982-0.993; P < 0.0001). Mean difference among three CCT consecutive measures, in the same eye, was 0.8 +/- 11.1 microm. High correlation was found between two users (ICC = 0.896; 95%IC 0.830-0.937; P < 0.0001). Z-CS4 CCT showed high correlation with US pachymetry (ICC = 0.921; 95%CI 0.851-0.958; P < 0.0001). Mean corneal thickness determined was statistically different with the two methods (US: 512.6 +/- 65.8 microm; z-CS4: 487.8 +/- 60.1 microm; P < 0.0001). Z-CS4 seems an accurate, noninvasive and reproducible technique for CCT evaluation and confirms that central cornea is thinner when measured with confocal microscopy compared to ultrasounds.
    Cornea 05/2007; 26(3):303-7. · 1.73 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

3 consecutive central corneal thickness measurements
 
93 patients
 
central corneal thickness values
 
experienced physician
 
interpreting central corneal thickness values
 
measurements
 
noncontact specular microscopy
 
Orbscan Topography System II
 
Pearson correlation coefficient
 
Researchers
 
Salt Lake City
 
scanning-slit corneal topography
 
Tokyo
 
Topcon SP-2000P noncontact specular microscope