Chagas cardiomyopathy and ischemic stroke

Neurology Department, Sarah Hospital, SMHS, CEP 7330-150, Brasilia DF, Brazil.
Expert Review of Cardiovascular Therapy 02/2006; 4(1):119-30. DOI: 10.1586/14779072.4.1.119
Source: PubMed


American trypanosomiasis, known as Chagas disease is a major cause of cardiomyopathy in South America. Irreversible damage to the heart can appear 10-20 years after chagasic infection. The relationship between Chagas cardiomyopathy and ischemic stroke has been reviewed. Significant variables that predict ischemic stroke in chagasic patients have been identified: apical aneurysm, cardiac insufficiency, electrocardiogram arrhythmia and female gender. Chagasic cardiomyopathy should be included in the differential diagnosis of the etiology of stroke, being a potential source of cardioembolic stroke.

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