"Very few cases of angiosarcoma of the prostate or seminal vesicle have been reported in the literature (Table 1).4-14 For angiosarcomas of the seminal vesicle, presenting symptoms may include testicular discomfort and perineal pain which may radiate to the lower back.11,13,14 Prostatic angiosarcoma can present with symptoms similar to prostatic adenocarcinoma, including dysuria, hematuria, or pelvic pain.7 Biopsy is required for definitive diagnosis. "
[Show abstract][Hide abstract] ABSTRACT: Angiosarcoma of the seminal vesicle is an extremely rare malignancy, with few published case reports in the literature. We present a case of primary angiosarcoma of the seminal vesicle in a 45-year-old male who was treated with multimodality therapy, consisting of neoadjuvant chemotherapy and chemoradiation followed by surgical resection and intraoperative radiation therapy. He has been free of cancer recurrence for more than six years after completion of therapy. To our knowledge, this represents the longest reported survival of a patient with this rare tumor, and one of the few cases reported using a multimodality therapy approach.
[Show abstract][Hide abstract] ABSTRACT: Among angiosarcomas, radiation-induced breast sarcomas (RIBS) represent a well-known entity generally characterized by a poor outcome, especially in patients with advanced disease. Despite the unfavorable prognosis, some chemotherapeutic agents have been used to treat these malignancies, occasionally with success. Treatments with demonstrated activity against sarcomas include ifosfamide-based regimens and, more recently, taxane derivatives. We report a case of a patient having a secondary breast angiosarcoma recurring early after surgery, who achieved complete remission following treatment with weekly paclitaxel. After 4 years of maintenance therapy, with an interval between consecutive administrations of no longer than 3 weeks, the patient is still in complete remission. A locoregional recurrence was documented twice during this period, the first as a consequence of a brief treatment interruption and the second because of a treatment delay. Nonetheless, in both instances a new complete remission was rapidly achieved with the resumption of the same treatment, without evidence of any significant adverse effects. We discuss the highly unusual behavior of this malignancy and the possible role of the two different mechanisms of action of paclitaxel-antiangiogenic versus cytotoxic-depending on the schedule of administration, with evidence of "false" drug-resistance.
[Show abstract][Hide abstract] ABSTRACT: In manufacturing processes, there are many manipulative operations
which deal with deformable objects. In this paper we analyse the dynamic
motion analysis of deformable rodlike objects. First, a geometric
representation to describe the shape of a rodlike object with dynamic
deformation is introduced. The potential and kinetic energy of the
object and the geometric constraints imposed on it are then formulated.
The shape of the dynamically deforming object can be derived by
minimizing the difference between the kinetic energy and potential
energy under the geometric constraints. Next, a procedure to compute the
deformed shape is developed by use of Euler's approach. Finally, some
numerical examples are shown in order to demonstrate how the proposed
approach computes the shapes of deformed rodlike objects
Intelligent Robots and Systems, 1997. IROS '97., Proceedings of the 1997 IEEE/RSJ International Conference on; 10/1997
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