[Show abstract][Hide abstract] ABSTRACT: A 49-year-old woman admitted to our hospital with a 3-month history of right flank pain without gross hematuria. Computed tomography scan of the abdomen showed that a 6x6x5 cm, contrast-enhanced mass was localized on the right renal pelvis. Histologically, a tumor composed of small ovoid to spindle shaped nuclei with indistinct cytoplasm was seen. Neoplastic cells showed diffuse immunoreactivity with CD34. It was diagnosed as solitary fibrous tumor. Solitary fibrous tumor of kidney is a very rare spindle cell neoplasm. It can mimic renal malignancy radiographically but almost all of renal solitary fibrous tumors are benign lesions. ÖZET Böbreğin soliter fibröz tümörü: bir olgu sunumu ve literatürün detaylı gözden geçirilmesi Kırk dokuz yaşındaki kadın hasta, gros hematüri olmaksızın 3 aydır süren sağ yan ağrısı şikayeti ile hastanemize başvurdu. Bilgisayarlı tomografide batında, sağ renal pelvis yerleşimli, kontrast tutan 6x6x5 cm boyutlarında kitle görüldü. Histolojik kesitlerde, küçük, iğsi-oval çekirdekli, sitoplazmik sı-nırları net olarak seçilemeyen hücrelerden oluşan tümör görüldü. Neoplastik hücreler CD34 ile kuvvetli immünreaktivite gösterdi. Lezyona soliter fibröz tümör tanısı konuldu. Böbreğin soliter fibröz tümörü, nadir görülen iğsi hüc-reli bir neoplazmdır. Radyolojik olarak renal maligniteleri taklit edebilir, ancak hemen tüm renal soliter fibröz tümörler benign lezyonlardır.
[Show abstract][Hide abstract] ABSTRACT: Solitary fibrous tumors are rare spindle cell neoplasms usually arising in the pleura. They have, however, also been reported at extrapleural locations. Solitary fibrous tumor (SFT) of the kidney is rare. Despite its rarity, histological diagnosis of solitary fibrous tumor is crucial to avoid misdiagnosis with other more aggressive tumors arising in the kidney. We report a solitary fibrous tumor of the left kidney that presented as a malignant tumor in a 51-year-old woman, and include clinical and radiographic findings. The tumor was well circumscribed and composed of spindle cells in a collagenous stroma. Immunohistochemistry showed reactivity for vimentin, CD 34, BCL-2 protein and CD99. Immunohistochemical stains for cytokeratin, S-100, desmin, alpha-smooth muscle actin and HMB-45 were negative. A diagnosis of SFT was made based on light microscopy and immunohistochemistry.
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.