Incidental hypoglobus: primary amyloidosis of the superior rectus.

The Eye Institute, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.
Singapore medical journal (Impact Factor: 0.6). 02/2006; 47(1):65-7.
Source: PubMed


A 69-year-old man who presented with incidental hypoglobus was found to have an isolated superior rectus mass. Diagnosis of primary amyloidosis of superior rectus was made on incisional biopsy and negative systemic work-up. This is an unusual manifestation and site for amyloidosis and should be a differential of any extraocular muscle mass.

113 Reads
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: We report a case of focal orbital amyloidosis involving rectus muscles, which is an extremely rare clinical condition. CT scans showed rectus muscle enlargement with punctate calcifications. Heterogeneous hypointensity was present on T2-weighted MR images, and homogeneous enhancement was seen on fat-saturated contrast-enhanced images of the muscles. These imaging findings seem to be suggestive of amyloidosis. Focal amyloidosis should be included in the differential diagnosis of extraocular muscle enlargement.
    American Journal of Neuroradiology 11/1998; 19(9):1799-801. · 3.59 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Fine needle aspiration (FNA) cytology of the orbit was used to diagnose an unusual case of multiple myeloma with secondary amyloid deposition in a 27-year-old man who presented with bilateral keratoconjunctivitis and left-sided ptosis. The FNA smears revealed immature plasma cells, extracellular eosinophilic material (amyloid) and numerous multinucleate giant cells. Subsequent histologic studies of excised tissue confirmed the cytologic diagnosis of plasmacytoma with secondary amyloidosis. Amyloid was further confirmed by electron microscopy. The patient was subsequently diagnosed as having multiple myeloma. The cytologic features of amyloidosis and plasmacytoma are presented. The differential diagnosis and the diagnostic utility of FNA cytology in the evaluation of these orbital lesions are also discussed. This apparently was the first case of orbital amyloidosis diagnosed by FNA cytology.
    Acta cytologica 01/1995; 39(1):104-10. · 1.56 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Primary, localised orbital amyloidosis has been reported previously in only 15 patients. A case with amyloidosis strictly localised to an extraocular muscle is presented.
    British Journal of Ophthalmology 02/1987; 71(1):32-3. DOI:10.1136/bjo.71.1.32 · 2.98 Impact Factor