Article

Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older.

Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101-1448, USA.
Annals of internal medicine (Impact Factor: 16.1). 02/2006; 144(2):73-81.
Source: PubMed

ABSTRACT Alzheimer disease and other dementing disorders are major sources of morbidity and mortality in aging societies. Proven strategies to delay onset or reduce risk for dementing disorders would be greatly beneficial.
To determine whether regular exercise is associated with a reduced risk for dementia and Alzheimer disease.
Prospective cohort study.
Group Health Cooperative, Seattle, Washington.
1740 persons older than age 65 years without cognitive impairment who scored above the 25th percentile on the Cognitive Ability Screening Instrument (CASI) in the Adult Changes in Thought study and who were followed biennially to identify incident dementia.
Baseline measurements, including exercise frequency, cognitive function, physical function, depression, health conditions, lifestyle characteristics, and other potential risk factors for dementia (for example, apolipoprotein E epsilon4); biennial assessment for dementia.
During a mean follow-up of 6.2 years (SD, 2.0), 158 participants developed dementia (107 developed Alzheimer disease). The incidence rate of dementia was 13.0 per 1000 person-years for participants who exercised 3 or more times per week compared with 19.7 per 1000 person-years for those who exercised fewer than 3 times per week. The age- and sex-adjusted hazard ratio of dementia was 0.62 (95% CI, 0.44 to 0.86; P = 0.004). The interaction between exercise and performance-based physical function was statistically significant (P = 0.013). The risk reduction associated with exercise was greater in those with lower performance levels. Similar results were observed in analyses restricted to participants with incident Alzheimer disease.
Exercise was measured by self-reported frequency. The study population had a relatively high proportion of regular exercisers at baseline.
These results suggest that regular exercise is associated with a delay in onset of dementia and Alzheimer disease, further supporting its value for elderly persons.

3 Followers
 · 
435 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Neurorehabilitation programs are commonly employed with the goal to help restore functionality in patients. However, many of these therapies report only having a small impact. In response to the need for more effective and innovative approaches, rehabilitative methods that take advantage of the neuroplastic properties of the brain have been used to aid with both physical and cognitive impairments. Following this path of reasoning, there has been a particular interest in the use of physical exercise as well as musical related activities. Although such therapies demonstrate potential, they also have limitations that may affect their use, calling for further exploration. Here, we propose dance as a potential parallel to physical and music therapies. Dance may be able to aid with both physical and cognitive impairments, particularly due to it combined nature of including both physical and cognitive stimulation. Not only does it incorporate physical and motor skill related activities, but it can also engage various cognitive functions such as perception, emotion, and memory, all while done in an enriched environment. Other more practical benefits, such as promoting adherence due to being enjoyable, are also discussed, along with the current literature on the application of dance as an intervention tool, as well as future directions required to evaluate the potential of dance as an alternative therapy in neurorehabilitation.
    Frontiers in Psychology 01/2014; 5:1478. DOI:10.3389/fpsyg.2014.01478 · 2.80 Impact Factor
  • Source
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Bu derlemenin amacı, egzersizin sağlık yararları hakkında güncel bilgileri gözden geçirmektir. Rehabilitasyon hekimliğinde, ayrıntılı reçetelendirilmiş egzersiz programı en önemli modalitedir. Bu yazıda, egzersizin özellikle kardiyovasküler hastalıklar, depresyon, demans, obezite ve günlük pratiğimizde sıklıkla görülen kronik ağrı sendromları üzerine olan sağlık yararları üzerinde durulmuştur. Egzersizin bu hastalıkların önlenmesi ve tedavisindeki önemli rolü incelenip, egzersiz önerileri derlenmiştir.The purpose of this review is to provide current information concerning the health benefits of exercise. In rehabilitation medicine, a detailed prescription of the exercise program is the most important modality. In this paper, the health benefits of exercise, especially on the cardiovascular diseases, depression, dementia, obesity, and chronic pain syndrome, frequently seen in our daily practice, are emphasized. The role of exercise in the prevention and treatment of these diseases is examined, and the recommendations for exercise are reviewed.
    FTR - Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi 10/2014; 60(Supp 2):9-14. DOI:10.5152/tftrd.2014.33716 · 0.08 Impact Factor

Full-text (2 Sources)

Download
589 Downloads
Available from
May 21, 2014