Article

One-year cost-effectiveness of surgical treatment of morbid obesity: vertical banded gastroplasty versus Lap-Band.

Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University, and Department of General Surgery, University Hospital Maastricht, The Netherlands.
Obesity Surgery (impact factor: 3.29). 02/2006; 16(1):75-84. DOI:10.1381/096089206775222113 pp.75-84
Source: PubMed

ABSTRACT This study was designed as an economic evaluation alongside a randomized clinical trial. The object of this study was to evaluate the 1-year cost-effectiveness of surgical treatment of morbid obesity comparing two operations.
100 patients were assigned randomly to vertical banded gastroplasty (VBG) or Lap-Band surgery. Both medical and non-medical costs were identified and measured. Costs data were combined with percentage Excess Weight Loss (%EWL) and with Quality Adjusted Life Years (QALYs) to obtain cost per %EWL and cost per QALY ratios.
At 1 year, the total costs were not significantly different between both groups (95% confidence interval E5,999-E1,765). Also, the QALY gain after surgery was not significantly different between the two groups. However, %EWL was significantly higher in the VBG group compared to the Lap-Band group, P-value .0001. The estimated incremental cost per %EWL was E105.83 (E1,885.91/-17.82). For the costs per QALY, the estimated ratio was dominant. The overall mortality in this study was 2%. 2 patients in the VBG group died within 30 days after surgery; 1 of these deaths was possibly related to the VBG procedure.
At 1 year after surgery, the costs and QoL of the two treatment modalities were found to be equal. Therefore, the selection of the procedure can be based on the clinical aspects, effectivity and safety at 1 year. In addition, the results of a long-term cost-effectiveness analysis (e.g. with a follow-up of 36 months) planned in the future can also be helpful in the selection of the preferred treatment.

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Keywords

1 year
 
1-year cost-effectiveness
 
2 patients
 
clinical aspects
 
costs
 
Costs data
 
economic evaluation
 
estimated incremental cost
 
estimated ratio
 
long-term cost-effectiveness analysis
 
non-medical costs
 
percentage Excess Weight Loss
 
QALY ratios
 
Quality Adjusted Life Years
 
randomized clinical trial
 
randomly
 
surgical treatment
 
total costs
 
two treatment modalities
 
vertical banded gastroplasty
 

Ghislaine A P G van Mastrigt