Recurrent Rhodococcus equi infection with fatal outcome in an immunocompetent patient
ABSTRACT The majority of human Rhodococcus equi infections occur in immunocompromised hosts, especially those with AIDS, and infection in immunocompetent patients is rare. Reported here is a case of R. equi infection in a seemingly healthy patient with a very complicated course. Despite neurosurgery and prolonged antibiotic therapy the patient deceased.
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Article: Cavitary pulmonary disease.[Show abstract] [Hide abstract]
ABSTRACT: A pulmonary cavity is a gas-filled area of the lung in the center of a nodule or area of consolidation and may be clinically observed by use of plain chest radiography or computed tomography. Cavities are present in a wide variety of infectious and noninfectious processes. This review discusses the differential diagnosis of pathological processes associated with lung cavities, focusing on infections associated with lung cavities. The goal is to provide the clinician and clinical microbiologist with an overview of the diseases most commonly associated with lung cavities, with attention to the epidemiology and clinical characteristics of the host.Clinical microbiology reviews 05/2008; 21(2):305-33, table of contents. DOI:10.1128/CMR.00060-07 · 16.00 Impact Factor
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ABSTRACT: A 35-year-old male presented with abdominal pain one month after receiving a routine ventral hernia repair. Over the course of two months, repeated wound cultures were ordered and eventually produced growth of Rhodococcus equi. Appropriate antibacterial therapy was initiated to resolve the infection.Clinical laboratory science: journal of the American Society for Medical Technology 01/2009; 22(3):141-5.
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ABSTRACT: To evaluate the carriage rates of Staphylococcus aureus and methicillin resistant Staphylococcus aureus (MRSA) in a university student population and describe risk factors associated with the carriage of each. Cross-sectional study (N = 203). Institutional Review Board approval was obtained from Texas State University-San Marcos. Texas State University-San Marcos, San Marcos, TX. Two-hundred and three university student samples were collected from December 2007 to July 2008. None indicated. The sample set was screened for S. aureus and MRSA identification by standard microbiological techniques and confirmed by use of a Vitek 2 per manufacturer recommendation. Antibiotic susceptibility testing was conducted on each MRSA isolate by Vitek 2. A questionnaire was conducted with each student to acquire demographic and risk factor information. Demographic data is shown by raw numbers, percentages, mean, and median where applicable. The compiled data was screened and analyzed by chi square (p values) and odds ratio (OR) with confidence interval (CI) to determine significance. Of the 203 participants who were screened, 60 (29.6%) carried S. aureus. Univariate analysis found that only hospitalization in the past 12 months was significantly associated with the risk of being a S. aureus carrier (OR=3.0, 95% CI 1.28-7.03). Of the 60 participants that carried S. aureus, 15 were identified as MRSA. This relates to a 7.4% MRSA carriage rate among generally healthy university students. Univariate analysis found that hospitalization in the past 12 months (OR = 4.2, 95% CI 1.29-13.36) and recent skin infection (OR = 4.4, 95% CI 1.07-18.24) were significantly associated with the risk of being a MRSA carrier. No unique antibiotic susceptibility patterns were identified with the MRSA isolates. The carriage rate of S. aureus is consistent with similar studies. MRSA carriage in this university study appears high as compared to the general population. Although this study did not confirm a variety of risk factors for carriage of MRSA previously identified by others, university healthcare personnel should be aware of the changing epidemiology of MRSA and preventive measures needed to avoid outbreaks.Clinical laboratory science: journal of the American Society for Medical Technology 01/2009; 22(3):176-84.