Prevalence of Four Developmental Disabilities Among Children Aged 8 Years—Metropolitan Atlanta Developmental Disabilities Surveillance Program, 1996 and 2000
ABSTRACT In the United States, developmental disabilities affect approximately 17% of children aged <18 years, resulting in substantial financial and social costs.
1996 and 2000.
The Metropolitan Atlanta Developmental Disabilities Surveillance Program (MADDSP) monitors the occurrence of mental retardation, cerebral palsy, hearing loss, vision impairment, and autism spectrum disorders among children aged 8 years in the five-county metropolitan Atlanta area (Clayton, Cobb, DeKalb, Fulton, and Gwinnett). MADDSP uses a multiple source ascertainment methodology.
During 1996, the prevalence of mental retardation was 15.5 per 1,000 children aged 8 years; it decreased to 12.0 per 1,000 in 2000. The overall prevalence of cerebral palsy was 3.6 per 1,000 in 1996 and 3.1 per 1,000 in 2000. The prevalence of mental retardation and cerebral palsy was highest among males and black children. The prevalence of hearing loss was 1.4 per 1,000 in 1996 and 1.2 per 1,000 in 2000; the prevalence of vision impairment during 1996 was 1.4 per 1,000 and 1.2 per 1,000 in 2000. Minimal differences by study year were observed in the prevalence of all four disabilities when examined by sex, race, and severity.
The prevalence of these four select developmental disabilities in MADDSP was higher in 1996 than the annual average prevalence estimates for these disabilities during previous MADDSP study years (1991-1994) study years; the highest increase was observed among children with mental retardation. However, prevalence estimates during 2000 were more consistent with the estimates from the early 1990s. Data from additional surveillance years (2002 and beyond) are needed to determine if the prevalence for 1996 was an anomaly and to continue to monitor trends in the prevalence of developmental disabilities over time.
MADDSP data will continue to be used to examine trends in the occurrence of these disabilities over time, facilitate the development and implementation of appropriate intervention programs, and provide a framework for conducting population-based etiologic studies.
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- "1985–1987 206 102,000 2.0 Slovenia Kavic & Perat, 1998  1981–1990 768 258,585 3.0 Northern Ireland Parks et al, 2001  1981–1993 982 445,464 2.20 Sweden: southern region Nordmark et al, 2001  1990–1993 167 65,514 2.2 US: metropolitan Atlanta Bhasin et al, 2006  1996–2000 268 80,815 5-year-olds 3.32 descriptive epidemiology of cp 255 "
ABSTRACT: The prevalence of cerebral palsy (CP) ranges from 1.5 to 2.5 per 1000 live births with little or no variation among western nations, although data from the Americas are sparse. Time trends in overall CP prevalence for the past 40 years are most notable for their stability, but a modest increase in prevalence probably occurred in the last decades of the twentieth century. European countries have pioneered the development of CP registries, and as a result, CP is a condition that is enumerated regularly in several parts of the world. The United States has no CP registries, although ongoing surveillance of CP, along with other developmental disabilities, is performed by the Centers for Disease Control and Prevention in metropolitan Atlanta.Clinics in Perinatology 07/2006; 33(2):251-67. DOI:10.1016/j.clp.2006.03.011 · 2.13 Impact Factor
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ABSTRACT: Subtelomeric rearrangements are an important cause of both sporadic and familial idiopathic mental retardation (MR) and/or congenital malformation syndromes. We report on a cohort of 107 children with idiopathic MR and normal karyotype 450-550 band level by GTG banding screened for subtelomeric rearrangements by multiprobe fluorescence in situ hybridization (FISH). In these cases, five patients had de novo deletions (1p deletion was found in 2 cases; 3q deletion, 9p and 9q deletions were found in 1 case each) and four patients had unbalanced rearrangements [der(5)t(5;15)(pter;qter)pat in 2 patients who were siblings, rec(10)dup(10p)inv(10)(p13q26)mat in 1 patient and der(18)t(18;22)(qter;qter) de novo in 1 patient]. Our study confirms that the subtelomeric rearrangements are a significant cause of idiopathic MR with dysmorphic features.The Turkish journal of pediatrics 51(5):453-9. · 0.56 Impact Factor