[Liver biopsy under guidance of multislice computed tomography: comparison of 16G and 18G biopsy needles].

Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Germany.
Der Radiologe (Impact Factor: 0.43). 06/2007; 47(5):430-8.
Source: PubMed

ABSTRACT Percutaneous cutting needle biopsy of focal liver lesions under CT guidance has established itself as a standard method. The purpose of this study was to evaluate which diagnostic quality can be achieved under guidance of multislice CT (MSCT) and with the use of different needle sizes.
The data of 163 MSCT-guided core biopsies of focal liver lesions were evaluated. A 16G biopsy needle was used in 121 cases and an 18G needle in 42 cases.
The sensitivity, specificity, and accuracy for all biopsies were 93.3, 100.0, and 94.5%. The corresponding values were 97.2, 100.0, and 97.5% for the 16G needle and 78.6, 100.0, and 85.7% for the 18G needle, respectively. A definite histological diagnosis could be obtained in 90.0% of the cases (16G 94.0%, 18G 75.8%). These differences were statistically highly significant. Bleeding complications were recognized in seven biopsies (4.3%). In one patient a fatal bleeding occurred after the biopsy. Median biopsy duration was 27 min.
Core biopsy under MSCT guidance is a fast and very accurate method to obtain a histological diagnosis in focal liver lesions. The usage of a 16G needle in comparison to an 18G needle yielded a significantly higher rate of correct results with regard to differentiation between benign and malignant disease as well as establishing a definite histological diagnosis. For an accurate diagnosis of liver lesions a 16G needle is recommended. After biopsy, the patients have to be closely monitored.

3 Reads
  • Article: The biopsy.
    [Show abstract] [Hide abstract]
    ABSTRACT: Conclusion Intestinal biopsy is a helpful procedure for the diagnosis of the diffuse lesions of the small intestine, but it is of limited value in cases of localized. Atrophy of the intestinal villi is characteristic to malabsorptive states, and lymphangiectasia of the intestinal mucosa to protein-losing entero pathy. Combined procedures of peroral intestinal biopsy and functional tests should be applied to secure the better diagnosis of intestinal lesions.
    Journal of oral surgery 11/1950; 8(4):342-8. DOI:10.1007/BF02779386
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The performance of a narrow-band interference rejection scheme using transform domain signal processing is studied in a hybrid DS/FH spread-spectrum system. The signal of interest can be considered to be a BPSK modulated direct-sequence spread-spectrum signal within one frequency hopping period. The interference itself is a narrow-band signal with a high power level and with a bandwidth relatively much narrower than the bandwidth of the wide-band signal. The interference can be located either intentionally or unintentionally within the DS-bandwidth which is centered according to the hopping frequency in question. The influence of the narrow-band interference will be reduced by using transform domain filtering. The interference excision takes place in the frequency domain after which the signal is transformed back to the time domain where the rest of the signal processing takes place. To avoid the dissemination of the interferer's energy over a wide frequency range, windowing is used prior to the transformation process. The transformations from the time domain to the frequency domain and vice versa are made by the fast Fourier transform (FFT) and the inverse fast Fourier transform (IFFT), respectively. The criterion used for the evaluation of the performance of the interference rejection algorithm is the bit error probability as a function of E<sub>b</sub>/N<sub>0</sub> and signal to jammer ratio (SJR). The bit error rates were obtained by Monte-Carlo simulations
    MILCOM 97 Proceedings; 12/1997
  • [Show abstract] [Hide abstract]
    ABSTRACT: Cross-sectional imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance (MR) imaging are well-accepted guiding tools for interventional biopsies and therapies (Gupta and Madoff 2007). Especially CT combined with fluoroscopy is able to offer fast and safe ways to nearly any target in the human body, incorporating the major advantage of panoramic views compared with ultrasound, and therefore represents very often the guiding modality of choice (Rogalla and Juran 2004). Even targets in bones and air-containing structures (e.g., lungs) can be addressed very easily and successfully with CT guidance. In contrast, MR imaging seems to be more complex and time-consuming and therefore is usually reserved for interventional procedures in very tricky areas with the necessity of high soft-tissue contrast and in situations where CT is contraindicated (Gupta 2004). The accuracy of the puncture and the complication rates depend on the target size and site, traversing and surrounding anatomical structures, the number of biopsies, the material and puncture technique selected, and patient’s cooperation (Gupta and Madoff 2007).
    12/2008: pages 55-68;
Show more

Hilmar Kuehl