Article

The correlation of midline shifts of human brain with large brain haematoma using a finite element approach.

Division of Neurosurgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.
Acta neurochirurgica. Supplement 02/2005; 95:363-5.
Source: PubMed

ABSTRACT We report on using a computational (finite element) model to simulate a human skull-brain structure to quantify the distortion of brain.
We simulated various effects of brain haematoma causing the distortion of brain. Midline shifts of the human brain in relation to size and location of haematoma were compared with the theoretical prediction.
Prediction of midline shifts in lobar space-occupying lesions was more accurate that in deep-seated ones (such as thalamic lesions).
More accurate boundary conditions of space-occupying lesions and better knowledge of physical materials properties of brain tissues can improve predictions of brain deformation using mathematical models.

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Keywords

brain haematoma
 
brain tissues
 
deep-seated ones
 
distortion
 
finite element
 
haematoma
 
human skull-brain structure
 
lobar space-occupying lesions
 
mathematical models
 
physical materials properties
 
predictions
 
simulate
 
space-occupying lesions
 
thalamic lesions
 
theoretical prediction