MR angiography fusion technique for treatment planning of intracranial arteriovenous malformations
ABSTRACT To develop an image fusion technique using elliptical centric contrast-enhanced (CE) MR angiography (MRA) and three-dimensional (3D) time-of-flight (TOF) acquisitions for radiosurgery treatment planning of arteriovenous malformations (AVMs).
CE and 3D-TOF MR angiograms with disparate in-plane fields of view (FOVs) were acquired, followed by k-space reformatting to provide equal voxel dimensions. Spatial domain addition was performed to provide a third, fused data volume. Spatial distortion was evaluated on an MRA phantom and provided slice-dependent and global distortion along the three physical dimensions of the MR scanner. In vivo validation was performed on 10 patients with intracranial AVMs prior to their conventional angiogram on the day of gamma knife radiosurgery.
Spatial distortion in the phantom within a volume of 14 x 14 x 3.2 cm(3) was less than +/-1 mm (+/-1 standard deviation (SD)) for CE and 3D-TOF data sets. Fused data volumes were successfully generated for all 10 patients.
Image fusion can be used to obtain high-resolution CE-MRA images of intracranial AVMs while keeping the fiducial markers needed for gamma knife radiosurgery planning. The spatial fidelity of these data is within the tolerance acceptable for daily quality control (QC) purposes and gamma knife treatment planning.
- [Show abstract] [Hide abstract]
ABSTRACT: Dural arteriovenous fistulas are characterized by abnormal arteriovenous shunting localized to the pachymeninges. Fistulae venous drainage is essential to their classification, symptomatology, and treatment. Endovascular therapy is rapidly progressing to an adjunct or even alternative treatment to microsurgical resection. Several techniques, such as transarterial or transvenous embolization with metallic coils, NBCA, or Onyx, have been used successfully in several studies. The long-term clinical and radiographic outcomes of endovascular therapy for the treatment of dural arteriovenous fistulas are satisfactory, and future studies are underway for the refinement of these techniques.Neurosurgery clinics of North America 10/2009; 20(4):431-9. DOI:10.1016/j.nec.2009.07.014 · 1.54 Impact Factor
Article: Preparation for Treatment Planning[Show abstract] [Hide abstract]
ABSTRACT: While most of this book is concerned with the Gamma Knife Perfexion, this chapter contains some notes relative to models Gamma Knife B, C and 4 C. This is because the relatively limited space within these models can result in the stereotactic frame or the patient’s head colliding with the helmet during treatment. This can make treatment impossible if necessary positions within the machine cannot be reached. A few simple principles will avoid this problem in nearly all cases. Occasionally, it is not possible to treat certain lesions and mention of this will be made during the chapter.
- [Show abstract] [Hide abstract]
ABSTRACT: Microsurgical resection of arteriovenous malformations (AVMs) is facilitated by real-time image guidance that demonstrates the precise size and location of the AVM nidus. Magnetic resonance images have routinely been used for intraoperative navigation, but there is no single MRI sequence that can provide all the details needed for characterization of the AVM. Additional information detailing the specific location of the feeding arteries and draining veins would be valuable during surgery, and this detail may be provided by fusing MR images and MR angiography (MRA) sequences. The current study describes the use of a technique that fuses contrast-enhanced MR images and 3D time-of-flight MR angiograms for intraoperative navigation in AVM resection. All patients undergoing microsurgical resection of AVMs at the Dartmouth Cerebrovascular Surgery Program were evaluated from the surgical database. Between 2009 and 2011, 15 patients underwent surgery in which this contrast-enhanced MRI and MRA fusion technique was used, and these patient form the population of the present study. Image fusion was successful in all 15 cases. The additional data manipulation required to fuse the image sets was performed on the morning of surgery with minimal added setup time. The navigation system accurately identified feeding arteries and draining veins during resection in all cases. There was minimal imaging-related artifact produced by embolic materials in AVMs that had been preoperatively embolized. Complete AVM obliteration was demonstrated on intraoperative angiography in all cases. Precise anatomical localization, as well as the ability to differentiate between arteries and veins during AVM microsurgery, is feasible with the aforementioned MRI/MRA fusion technique. The technique provides important information that is beneficial to preoperative planning, intraoperative navigation, and successful AVM resection.Neurosurgical FOCUS 05/2012; 32(5):E7. DOI:10.3171/2012.1.FOCUS127 · 2.14 Impact Factor