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Steroid-induced psychosis treated with valproic acid and risperidone in a patient with systemic lupus erythematosus.

The Primary Care Companion to The Journal of Clinical Psychiatry 02/2005; 7(6):312. DOI: 10.4088/PCC.v07n0610b
Source: PubMed
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    ABSTRACT: We previously reported a case in which steroid-induced psychosis was eliminated with risperidone treatment in a patient with polyarteritis nodosa (PN). In the present report, we longitudinally tracked the serum levels of brain-derived neurotrophic factor (BDNF). We found that corticosteroid lowered serum BDNF levels, and improvement of psychiatric symptoms was intact with the serum BDNF levels seen in the patients.
    Annals of General Psychiatry 01/2012; 11(1):2. DOI:10.1186/1744-859X-11-2 · 1.53 Impact Factor
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    ABSTRACT: Introduction: Psychotic disorders induced by corticosteroids have an unpredictable course and in the majority of cases do not follow a specifi c clinical pattern. This may hinder the diagnosis and treatment of this pathology. The objective is to discuss psychopathological fi ndings, therapeutical approaches and prognosis of steroid-induced psychotic disorders. Method: Case report. Results: The case describes a man who was receiving inpatient treatment in the intensive care unit following a severe asthma crisis and during the hospitalization had an acute psychotic episode related to high doses of steroids. He had an adequate res-ponse to quetiapine and the progressive reduction of steroids. Conclusions: Steroid-induced psychotic disorders have diverse phenomenological fi ndings that require careful appraisal. In general terms, they resolve rapidly when the doses are reduced and hwith the use of antipsychotics.
    01/2007; XXXVI(3):542-550.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Psychotic disorders induced by corticosteroids have an unpredictable course and in the majority of cases do not follow a specifi c clinical pattern. This may hinder the diagnosis and treatment of this pathology. The objective is to discuss psychopathological fi ndings, therapeutical approaches and prognosis of steroid-induced psychotic disorders. Method: Case report. Results: The case describes a man who was receiving inpatient treatment in the intensive care unit following a severe asthma crisis and during the hospitalization had an acute psychotic episode related to high doses of steroids. He had an adequate response to quetiapine and the progressive reduction of steroids. Conclusions: Steroid-induced psychotic disorders have diverse phenomenological fi ndings that require careful appraisal. In general terms, they resolve rapidly when the doses are reduced and hwith the use of antipsychotics.
    09/2007; 36(3):542-550.

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