Epithelioid hemangioma of bone: a potentially metastasizing tumor?
ABSTRACT The case of a 15-year-old boy with a severe swelling of the 2nd toe in the left foot and a large swelling of the left inguinofemoral region is described. Histologic examination of the foot lesion showed a typical epithelioid hemangioma of bone that extended into the soft tissues, with a secondary location in the groin, suggestive of lymph node involvement. Subsequently, imaging also revealed swelling of iliac and para-aortic lymph nodes, which probably indicates further lymph node spread.. Besides the fact that epithelioid hemangioma of the toe has not been reported yet, our case showed a non-continuous localization, most likely in draining lymph nodes. This finding suggests metastatic disease, an event that is extremely rare for epithelioid hemangioma. As such, epithelioid hemangioma might be comparable to another benign vascular tumor, the retiform hemangioendothelioma, which occasionally metastasizes to the lymph nodes without systemic spread.
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ABSTRACT: Presented is a case of epithelioid hemangioma (EH) of bone occurring in the radial styloid of a 17-year-old boy. EH is a rare benign vascular tumor whose name and classification have changed over the years, adding potential confusion to an already existing diagnostic challenge. Overlapping imaging and histopathologic features with other malignant vascular neoplasms and occasional aggressive clinical features such as multifocal disease or lymph node involvement have resulted in misdiagnoses and inappropriate treatment. The goal of this case report is to raise awareness of EH and related vascular neoplasms.Clinical Imaging 11/2014; · 0.60 Impact Factor
- Journal de Radiologie 11/2010; 91(11):1158–1160. · 0.57 Impact Factor
Article: Vascular Tumors of Bone[Show abstract] [Hide abstract]
ABSTRACT: Vascular tumors of bone represent a variety of neoplasms, ranging from benign hemangiomas and epithelioid hemangiomas, to intermediate grade hemangioendotheliomas, to frankly malignant angiosarcomas. Over the years, there has been considerable debate concerning the aggressivity, nomenclature and mere existence of various nosologic entities, due to morphologic similarities and uncertainty regarding biologic behavior. Such debate has led to confusion among pathologists and clinicians, thus diminishing the prognostic implications in the diagnosis of these lesions. Here we review the current knowledge concerning the primary vascular neoplasms of bone, and correlate clinicopathologic features with tumor behavior.Seminars in Diagnostic Pathology 01/2014; · 1.80 Impact Factor