Article

Comparison of the methyl ester of L-tyrosine hydrochloride and its methanol monosolvate.

Faculty of Chemistry, University of Wrocław, 14 Joliot-Curie Street, 50-383 Wrocław, Poland.
Acta Crystallographica Section C Crystal Structure Communications (impact factor: 0.52). 04/2006; 62(Pt 3):o111-4. DOI:10.1107/S0108270106002137 pp.o111-4
Source: PubMed

ABSTRACT Solvent-free (2S)-methyl 2-ammonio-3-(4-hydroxyphenyl)propionate chloride, C10H14NO3+.Cl-, (I), and its methanol solvate, C10H14NO3+.Cl-.CH3OH, (II), are obtained from different solvents: crystallization from ethanol or propan-2-ol gives the same solvent-free crystals of (I) in both cases, while crystals of (II) were obtained by crystallization from methanol. The structure of (I) is characterized by the presence of two-dimensional layers linked together by N-H...Cl and O-H...Cl hydrogen bonds and also by C-H...O contacts. Incorporation of the methanol solvent molecule in (II) introduces additional O-H...O hydrogen bonds linking the two-dimensional layers, resulting in the formation of a three-dimensional network.

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Keywords

C-H...O contacts
 
crystallization
 
crystals
 
different solvents
 
methanol
 
methanol solvate
 
methanol solvent molecule
 
O-H...Cl hydrogen bonds
 
Solvent-free
 
solvent-free crystals
 
three-dimensional network
 
two-dimensional layers
 

Iwona Bryndal