Association of depression and anxiety disorders with weight change in a prospective community-based study of children followed up into adulthood
ABSTRACT To investigate childhood to adulthood weight change associated with anxiety and depression.
The Children in the Community Study. A prospective longitudinal investigation.
Albany and Saratoga Counties, New York.
Eight hundred twenty individuals (403 females and 417 males) assessed at 4 time points: in 1983 when they were 9 to 18 years old (n = 776), in 1985 to 1986 when they were 11 to 22 years old (n = 775), in 1991 to 1994 when they were 17 to 28 years old (n = 776), and in 2001 to 2003 when they were 28 to 40 years old (n = 661).
Anxiety disorders and depression assessed by structured diagnostic interview.
Centers for Disease Control and Prevention body mass index z score (BMIz), a measure of weight status; and association of anxiety and depression with BMIz level and annual change.
In females, anxiety disorders were associated with higher weight status, a BMIz of 0.13 (95% confidence interval, 0.01-0.25) units higher compared with females without anxiety disorders. Female depression was associated with a gain in BMIz of 0.09 units/y (95% confidence interval, 0.03-0.15 units/y), modified by the age when depression was first observed, such that early depression onset was associated with a higher subsequent BMIz than depression onset at older ages. In males, childhood depression was associated with a lower BMIz (-0.46; 95% confidence interval, -0.93 to 0.02 units lower at the age of 9 years), but BMIz trajectories for males with or without depression converged in adulthood; male anxiety disorders were not substantively associated with weight status.
Anxiety disorders and depression were associated with a higher BMIz in females, whereas these disorders in males were not associated with a higher BMIz. These results, if causal and confirmed in other prospective studies, support treating female anxiety and depression as part of comprehensive obesity prevention efforts.
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ABSTRACT: Adolescence is often a challenging time, and these challenges become more daunting for children who live in poverty. Access to health care is an issue for these teens, and limited funds as well as the ability to get to health centers create further barriers, especially for preventive health care services. Adolescents today face many health care issues that will have a profound effect on their lives. The increased incidence of obesity and the subsequent morbidities such as type 2 diabetes will have lifelong effects on their health. The rising incidence of significant mental health disorders affects not only their ability to be successful in school but also their capability to function as independent adults. School-based health centers (SBHCs) are an innovative health delivery model that is ideally situated to address these morbidities. This article summarizes the health problems teens are facing in 2007 and the creative ways some SBHCs have addressed these problems.The Journal for Nurse Practitioners 11/2007; 3(10):713-720. DOI:10.1016/j.nurpra.2007.08.025
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ABSTRACT: Given the limited empirical data on antidepressant use and weight change in children, we performed a historical cohort study to assess change in age- and sex-standardized body mass index associated with antidepressant use among overweight adolescents diagnosed with a depressive disorder. We systematically reviewed electronic medical records from a tertiary academic medical center and identified adolescents (age 13-18 years) who were overweight (body mass index >85th percentile) and had a depression diagnosis. Patients were seen from January 1, 2000, through January 1, 2010. Age- and sex-standardized body mass index scores were calculated at initiation of antidepressant medication and at the end of treatment. Unmedicated patients had baseline and final age- and sex-standardized body mass index calculated using the first and last recorded measurements in the study period (maximum time between measures was 5 years). In total, 435 patients (301 female) met our inclusion criteria; of these, 255 were prescribed an antidepressant (selective serotonin reuptake inhibitor, serotonin norepinephrine reuptake inhibitor, tricyclic antidepressant, or dopamine-norepinephrine reuptake inhibitor). Age- and sex-standardized body mass index significantly increased (F1,193=14.34; P<0.001) only for adolescents treated with selective serotonin reuptake inhibitors. For patients receiving other medications or no medication, age- and sex-standardized body mass index did not change significantly. This study provides initial empiric evidence for a link between selective serotonin reuptake inhibitor use and weight gain in already overweight adolescents. Further study of antidepressant use and weight gain in other pediatric populations and in prospective studies is warranted.Innovations in Clinical Neuroscience 11/2014; 11(11-12):14-21.
Wellbeing 2011, International Conference Exploring Multi-dimensions of Well-being, Birmingham City University and the Royal Institute of British Architects (RIBA); 07/2011