Multisegment and Halfscan Reconstruction of 16-Slice Computed Tomography for Assessment of Regional and Global Left Ventricular Myocardial Function

Department of Radiology, Freie Universität and Humboldt-Universität zu Berlin, Germany.
Investigative Radiology (Impact Factor: 4.44). 04/2006; 41(4):400-9. DOI: 10.1097/01.rli.0000201233.42994.9b
Source: PubMed


We sought to prospectively compare multisegment and halfscan reconstruction of 16-slice computed tomography (CT) for the assessment of regional and global left ventricular myocardial function with magnetic resonance imaging (MRI) as the reference standard.
Forty-two patients underwent CT with 16 x 0.5-mm detector collimation. Electrocardiogram-gated reconstructions were generated with multisegment reconstruction (using up to 4 segments correlated with the raw data of up to 4 heartbeats) and standard halfscan reconstruction. Steady-state free-precession cine MRI was acquired within 24 hours.
More normal myocardial segments were identified correctly with multisegment (95%, 620/656) compared with halfscan reconstruction (88%, 582/656) of CT (P < 0.001). Also, the accuracy (92% [657/714] vs. 87% [620/714]) and rate of nondiagnostic segments (0% vs. 5% [33/714]) were significantly better when using multisegment reconstruction (P < 0.001). The image quality with multisegment reconstruction was significantly superior to that achieved with halfscan reconstruction (P < 0.001). In the assessment of global left ventricular function, multisegment and halfscan reconstruction of CT showed high correlations for all parameters with MRI, whereas Bland-Altman analysis revealed smaller limits of agreement for assessment of myocardial mass with multisegment reconstruction (P = 0.025), but no significant differences between both reconstruction techniques in the measurement of left ventricular volumes as compared with MRI.
Multisegment reconstruction of 16-detector row CT improves image quality and assessment of regional wall motion compared with standard halfscan reconstruction.

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    • "Scanning was performed on an MSCT scanner using 16 × 0.5 mm detector collimation (Aquilion 16, Toshiba Medical Systems, Otawara, Japan) as recently described [11] with retrospective ECG gating, multisegment reconstruction [7,13], 0.4 s rotation time, 120 kV, 300 mA, and 0.2 pitch, and an average image reconstruction interval of 146 ms, which was not significantly different between women (149 ± 36 ms) and men (146 ± 37 ms). Nitrate was administered prior to MSCT to increase the coronary artery diameters and to facilitate image assessment [14]. "
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