Previous studies examining the reliability of self-reported Tanner stages have given conflicting results. We report on the reliability of self-reported Tanner stages in lean healthy children.
Self-reported Tanner staging of 240 children (130 girls, 110 boys) were compared to the ratings of a pediatric endocrinologist who was unaware of the children's self-assessments. The correlation between the two approaches was analyzed using kappa statistics.
40% (kappa coeffcient = 0.49, p <0.001) and 23% (kappa coefficient = 0.68, p <0.001) of the girls rated their breast and pubic Tanner stage incorrectly, respectively; 39% of the boys (kappa coefficient = 0.49, p <0.001) rated their pubic stage incorrectly. The age of the children who self-rated correctly and incorrectly was not different; no independent predictors for correct Tanner staging self-assessment were found.
The results of this analysis suggest that self-rated Tanner pubertal staging is not influenced by age and is not a reliable method of assessing Tanner stage.
"Furthermore, in order to better monitor any potential neurological adverse effects, we used the validated Spanish versions of the modified Simpson- Angus Scale (SAS) (Simpson and Angus 1970) and the Abnormal Involuntary Movement Scale (AIMS) (Guy 1976). Further, the risk for metabolic syndrome, cardiovascular, cardiac, endocrine and other relevant adverse events are specifically monitored through complete physical examination , including height, weight, body mass index (BMI) and waist circumference, and sexual development, assessed using Tanner staging (Desmangles et al. 2006); an electrocardiogram (PR and QTc intervals), systolic and diastolic blood pressure and pulse rate, respectively. Finally, fasting blood work is obtained for full blood count, coagulation, serum glucose, electrolytes, hepatic and renal function tests, lipid profile, insulin, thyroid hormones, sex hormones, and prolactin. "
[Show abstract][Hide abstract] ABSTRACT: Despite drastic increases in antipsychotic prescribing in youth, data are still limited regarding their safety in this vulnerable population, necessitating additional tools for capturing long-term, real world data.
We present SENTIA (SafEty of NeurolepTics in Infancy and Adolescence; https://SENTIA.es), an online registry created in 2010 to track antipsychotic adverse effects in Spanish youth <18 years old currently taking or initiating with any antipsychotic treatment. SENTIA collects information on sociodemographic, diagnostic and treatment characteristics, past personal medical/psychiatric history, healthy lifestyle habits and treatment adherence. Additionally, efficacy and adverse effect data are recorded including the Children's Global Assessment Scale; Clinical Global Impressions scale for Severity and Improvement, the Safety Monitoring Uniform Report Form, Simpson-Angus Scale, Abnormal Involuntary Movement Scale, vital signs, blood pressure, and EKG. Finally, fasting blood is drawn for hematology, electrolytes, renal, liver and thyroid function, glucose, insulin, lipid, prolactin and sex hormone levels. Initially, a diagnostic interview and several psychopathology scales were also included. Patients are assessed regularly and followed even beyond stopping antipsychotics.
Since 01/17/2011, 85 youth (11.5 ± 2.9 (range = 4-17) years old, 70.6% male) have been included at one inaugural center. After a mean duration of 17 ± 11 (range = 1-34) months, 78.8% are still actively followed. For feasibility reasons, the diagnostic interview and detailed psychopathology scales were dropped. The remaining data can be entered in <30 minutes. Several additional centers are currently being added to SENTIA.
Implementation of a systematic online pharmacovigilance system for antipsychotic adverse effects in youth is feasible and promises to generate important information.
"Higher scores indicate higher Tanner stage, thus more advanced maturation. Although under-and overestimations of Tanner stage occur (Schlossberger et al. 1992; Desmangles et al. 2006), several studies have confirmed adequate reliability and validity for the use of self-reported Tanner schematics in studies that seek to examine approximations of development (Brooks-Gunn et al. 1987; Schmitz et al. 2004). In the context of this large-scale cohort study, this form of assessment was more practical than other approaches (e.g., physician examination), and was advantageous in terms of low invasiveness and privacy. "
[Show abstract][Hide abstract] ABSTRACT: Extensive evidence supports associations between early pubertal timing and adolescent externalizing behavior, but how and under which conditions they are linked is not fully understood. In addition, pubertal development is also characterized by variations in the relative speed at which individuals mature, but studies linking pubertal 'tempo' and outcomes are scarce. This study examined the mediating and moderating roles of spare time activities in associations between pubertal development and later delinquency, using data from a large (4,327 girls, 4,250 boys) longitudinal UK cohort (Avon Longitudinal Study of Parents and Children). Self-reports of Tanner stage were available from ages 9 to 14, spare time activities at age 12 and delinquency at age 15. Pubertal development was examined using latent growth models. Spare time activities were categorized using factor analyses, yielding four types (hanging out at home, hanging out outside, consumerist behavior, and sports/games), which were examined as mediators and moderators. Earlier and faster maturation predicted delinquency in boys and girls. Spare time activities partially mediated these links such that early maturing girls more often engaged in hanging out outside, which placed them at greater risk for delinquency. In addition, compared to their later and slower maturing counterparts, boys who matured earlier and faster were less likely to engage in sports/games, a spare time activity type that is linked to lower delinquency risk. No moderation effects were found. The findings extend previous research on outcomes of early maturation and show how spare time activities act as proxies between pubertal development and delinquency.
Journal of Youth and Adolescence 12/2013; 43(8). DOI:10.1007/s10964-013-0074-7 · 2.72 Impact Factor
"Desmangles et al used the Tanner staging of pubic hair distribution in self-assessment of pubertal development in boy students. They reported that higher rate of underestimation was seen in late puberty, whereas patients in earlier pubertal stages were more prone to overestimate themselves. "
[Show abstract][Hide abstract] ABSTRACT: This investigation aims to evaluate the validity of a Persian Tanner Stages Self-Assessment Questionnaire.
In this cross sectional study, 190 male students aged 8-16 years selected from three layers of different regions of Tehran (North, Central and South) were enrolled. A Persian questionnaire illustrated with Tanner stages of puberty (genital development and pubic hair distribution) was prepared. Children were asked to select the illustration that best described their pubertal development. Tanner status of the children was also estimated by an independent physician using physical examination. The degree of agreement between subjects' judgments with assessments made by the rater was compared through the calculation of the weighted kappa statistic coefficient.
We found a substantial agreement between self-assessment of pubertal development made by the children and doctor's assessment of genital development (kappa=0.63, P<0.0001) and also the pubic hair distribution (kappa= 0.74, P<0.0001). Although a large proportion of subjects in G4 (89.2%) and G5 (85.7%) were capable of accurately or almost accurately identifying their own Tanner sexual stages, some degree of disagreement was observed in G3 Tanner stage (%46.9).
Self-assessment of puberty should be used very cautiously and may not be a substitute method for routine evaluation of pubertal state especially for early and mid pubertal groups.
Iranian Journal of Pediatrics 06/2013; 23(3):327-32. · 0.52 Impact Factor
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