Pulmonary vein stenosis following repair of total anomalous pulmonary venous connection.

Section of Cardiac Surgery, Division of Pediatric Cardiac Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
Pediatric Cardiac Surgery Annual of the Seminars in Thoracic and Cardiovascular Surgery 02/2006; DOI: 10.1053/j.pcsu.2006.02.023
Source: PubMed

ABSTRACT Pulmonary vein stenosis may occur following the repair of total anomalous pulmonary venous connection and carries a poor prognosis. Conventional surgical therapies have been complicated by a high rate of re-stenosis. Sutureless pericardial marsupialization has been introduced as a technique to reduce the rate of re-stenosis. This report describes a retrospective review of a group of patients undergoing repair of acquired pulmonary vein stenosis. Presence of single-ventricle anatomy was found to be the primary preoperative risk factor for a poor outcome. The use of sutureless pericardial marsupialization was found to be associated with a significant improvement in disease-free survival.

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    ABSTRACT: Surgical correction of total anomalous pulmonary venous connection (TAPVC) remains a challenge, with reported early mortality rates of up to 20 %. In this review article, we describe several topics, including surgery for neonates, diagnoses with multidetector computed tomography (MDCT), and primary sutureless repair. Several studies have reported mortality rates of around 10 %, and demonstrated unchanged hospital mortality in neonates, despite improvement of the overall mortality of cohorts including older patients. Previous reports identified a low body weight at the time of the operation, preoperative pulmonary venous obstruction (PVO), and a prolonged cardiopulmonary bypass time as risk factors for hospital mortality. With the development of new technologies, MDCT has become a good diagnostic modality for use in the pre- and post-operative evaluation. MDCT delineates the drainage site of the vertical vein and the atypical vessel into the systemic vein, and it can also evaluate the existence of obstruction in the vertical vein. Following favorable experiences with post-repair PVO, the indications for sutureless repair as a primary operation have been expanded for infants, including those at risk of developing PVO after the repair of TAPVC. Primary sutureless repair has proven especially useful for difficult patient groups, such as those with congenital PVO, infracardiac TAPVC with small pulmonary veins, or mixed-type TAPVC.
    Surgery Today 03/2014; 44(12). DOI:10.1007/s00595-014-0877-5 · 1.21 Impact Factor
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    ABSTRACT: Active perioperative intervention and improvement on surgical technique has decreased the mortality rate of total anomalous pulmonary venous connection (TAPVC); however, when complicated with pulmonary venous obstruction, operative mortality is still high. The purpose of this study was to investigate the clinical course of TAPVC.
    Korean Journal of Pediatrics 01/2009; 52(2). DOI:10.3345/kjp.2009.52.2.194
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    ABSTRACT: Background. Pulmonary vein stenosis (PVS), both congenital and acquired, is challenging to treat surgically with uncertain long-term results. We reviewed an 11-year surgical experience in 52 children. Methods. From 2002 to 2012, 52 children age 0 days to 13 years (mean 1.9 years, median 11.7 months) weighing 2.2 to 32.5 kg (mean 9.3 kg, median 7.6 kg) had surgical relief of PVS. Based on clinical characteristics or complexity, 33 (63%) had a sutureless pericardial well repair and 19 (37%) had a more standard patch repair. There were no significant differences in clinical characteristics between the 2 techniques. Twenty children (38%) had prior anomalous pulmonary vein repair and 8 had primary pulmonary vein stenosis; 26 (50%) had other operations at the time of PVS relief. Results. There were 2 hospital deaths (10.5%) in the "standard" group and 5 (15.2%) in the sutureless group (p > 0.99). Despite postoperative evidence of PVS relief by echocardiogram or cardiac cath in all patients, at 5 years, actuarial freedom from PVS recurrence or death in the hospital survivors was 67% in the standard group and 58% in the sutureless group. Most recurrences or deaths occurred within 6 months of operation. Heterotaxy, single ventricle anatomy, bilateral disease, and previous anomalous pulmonary vein repair were not predictors of failure. Conclusions. Surgical treatment of pulmonary vein stenosis remains a challenging problem with nontrivial early mortality and ongoing risk for recurrence or death regardless of surgical technique employed. Clearly, development of methods for earlier intervention or detection and improved surgical techniques are warranted. (C) 2014 by The Society of Thoracic Surgeons
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