Corrosive induced carcinoma of esophagus: Report of three patients and review of literature
ABSTRACT Patients with corrosive induced esophageal strictures have more than a 1000-fold risk of developing carcinoma of the esophagus. We report three cases of corrosion carcinoma seen by us (a team of gastroenterologists, radiologists and a surgeon) in the last 15 years. Two cases were among 156 patients with corrosive induced strictures on our follow-up, and constituted the only corrosion carcinoma out of 650 esophageal carcinomas operated on by us. Nearly all reported patients with corrosion carcinoma in the published literature had consumed an alkali, but two of our three patients had consumed an acid.
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ABSTRACT: The two main histological esophageal cancer types, adenocarcinoma and squamous cell carcinoma, differ in incidence, geographic distribution, ethnic pattern and etiology. This article focuses on epidemiology with particular reference to geographic and temporal variations in incidence, along with a review of the evidence supporting environmental and genetic factors involved in esophageal carcinogenesis. Squamous cell carcinoma of the esophagus remains predominantly a disease of the developing world. In contrast, esophageal adenocarcinoma is mainly a disease of western developed societies, associated with obesity and gastro-esophageal reflux disease. There has been a dramatic increase in the incidence of adenocarcinoma in developed countries in parallel with migration of both esophageal and gastric adenocarcinomas towards the gastro-esophageal junction.09/2010; 2(3):1379-1404. DOI:10.3390/cancers2031379
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ABSTRACT: Esophagitis is a frequent cause of clinical symptoms and is often an indication for upper endoscopy. Mucosal biopsies are procured for diagnostic purposes and may be used to assess the efficacy of treatment, as in patients with eosinophilic esophagitis. This manuscript outlines salient clinical and pathologic features of diseases that cause esophagitis exclusive of reflux esophagitis.Seminars in Diagnostic Pathology 03/2014; DOI:10.1053/j.semdp.2014.02.002 · 1.80 Impact Factor
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ABSTRACT: A 29-year-old woman who swallowed oil cleaner (strong hydroxide: NaOH) by mistake received conservative therapy because of having neither mediastinitis nor peritonitis. She complained of dysphagia 1 month after ingestion. Upper gastrointestinal series showed severe stricture in the middle and lower thoracic esophagus and in the antrum of the stomach. Gastrostomy and jejunostomy were performed on the 87th day after ingestion. Transthoracic subtotal esophagectomy and total gastrectomy followed by esophageal reconstruction using the colon with microvascular anastomosis through a retrosternal route was performed on the 148th day after the ingestion. On open thoracotomy, although dense mediastinal adhesions were found around the esophagus, esophagectomy could be achieved successfully. She was discharged 22 days after the second surgery without postoperative complication.Esophagus 09/2012; 9(3). DOI:10.1007/s10388-012-0313-0 · 0.74 Impact Factor