Tamm-Horsfall protein knockout mice do not develop medullary cystic kidney disease

Oklahoma City University, Oklahoma City, Oklahoma, United States
Kidney International (Impact Factor: 8.56). 06/2006; 69(10):1914-5. DOI: 10.1038/
Source: PubMed
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    • "Umod encodes the glycoprotein uromodulin, and its expression is widely used as a marker of the adult DT and LH segments [78]. Umod knockout mice do not display a phenotype [79], but Umod mutation in humans results in hyperuricemic nephropathy and medullary cystic kidney disease type 2 [80]. "
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