Bartonella Spp. in Pets and Effect on Human Health

Department of Population Health and Reproduction, University of California School of Veterinary Medicine, Davis, California 95616, USA.
Emerging infectious diseases (Impact Factor: 6.75). 04/2006; 12(3):389-94. DOI: 10.3201/eid1205.050931
Source: PubMed


Among the many mammals infected with Bartonella spp., pets represent a large reservoir for human infection because most Bartonella spp. infecting them are zoonotic. Cats are the main reservoir for Bartonella henselae, B. clarridgeiae, and B. koehlerae. Dogs can be infected with B. vinsonii subsp. berkhoffii, B. henselae, B. clarridgeiae, B. washoensis, B. elizabethae, and B. quintana. The role of dogs as an important reservoir of Bartonella spp. is less clear than for cats because domestic dogs are more likely to be accidental hosts, at least in nontropical regions. Nevertheless, dogs are excellent sentinels for human infections because a similar disease spectrum develops in dogs. Transmission of B. henselae by cat fleas is better understood, although new potential vectors (ticks and biting flies) have been identified. We review current knowledge on the etiologic agents, clinical features, and epidemiologic characteristics of these emerging zoonoses.

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    • "These fleas are common on dogs and can also feed on humans; therefore, this genus may be considered an important vector of Bartonella spp., and dogs would be a potential source of this zoonotic agent to humans (Yore et al. 2014). Two C. felis pools from cats were positive for B. henselae or B. clarridgeiae , which are frequently associated with feline hosts, but can be transmitted to dogs and humans (Chomel et al. 2006). "
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    ABSTRACT: The bacterial genus Bartonella includes several species with zoonotic potential, some of which are common in domestic dogs and cats, as well as in their fleas. Because there is no previous information about the presence of Bartonella species in fleas from Central America, this study aimed at evaluating the presence of Bartonella spp. in fleas collected from dogs and cats in Costa Rica. A total 72 pools of Ctenocephalides felis and 21 pools of Pulex simulans were screened by conventional PCR to detect Bartonella DNA fragments of the citrate synthase (gltA) and the β subunit RNA polymerase (rpoB) genes. Three (4.2%) pools of C. felis and five pools (22.7%) of P. simulans were found positive for Bartonella DNA. Sequences corresponding to Bartonella vinsonii subsp. berkhoffii strain Winnie, B. rochalimae, and an undescribed Bartonella sp. (clone BR10) were detected in flea pools from dogs, whereas Bartonella henselae and B. clarridgeiae sequences were identified in flea pools from cats. The detection of zoonotic Bartonella spp. in this study should increase the awareness to these flea-borne diseases among physicians and public health workers and highlight the importance of flea control in the region.
    Vector borne and zoonotic diseases (Larchmont, N.Y.) 09/2015; 15(10). DOI:10.1089/vbz.2015.1799 · 2.30 Impact Factor
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    • "including Bartonella rochalimae, Bartonella koehlerae, Bartonella bovis, and Bartonella quintana (Kordick et al. 1999, Sander et al. 1999, Breitschwerdt 2008, Kaiser et al. 2011). Domestic dogs are believed to be one of the reservoirs for Bartonella vinsonii subspecies berkhoffii (Breitschwerdt et al. 2010, Diniz et al. 2013, Chomel et al. 2014) and can also be infected with B. henselae, B. clarridgeiae, and B. rochalimae, like domestic cats (Mexas et al. 2002; Chomel et al. 2006, 2014; Kaiser et al. 2011; Brenner et al. 2013). "
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    ABSTRACT: In the present study, we investigated 238 fleas collected from cats and dogs in three regions of Peru (Ancash, Cajamarca, and Lima) for the presence of Bartonella DNA. Bartonella spp. were detected by amplification of the citrate synthase gene (16.4%) and the 16S-23S intergenic spacer region (20.6%). Bartonella rochalimae was the most common species detected followed by Bartonella clarridgeiae and Bartonella henselae. Our results demonstrate that dogs and cats in Peru are infested with fleas harboring zoonotic Bartonella spp. and these infected fleas could pose a disease risk for humans.
    Journal of Medical Entomology 09/2015; DOI:10.1093/jme/tjv137 · 1.95 Impact Factor
    • "Albeit the detection of Bartonella spp. and Leishmania spp. in ticks had already been reported, the role of ticks in the transmission of these pathogens has yet to be confirmed (Chomel et al., 2006; Otranto et al., 2009; Trotta et al., 2012). In this study, like in the one performed by Toledo et al. (2009), in central Spain, no Bartonella or Leishmania DNA was found in ticks, indicating that, at least in the surveyed districts, they do not seem to play a role in the cycle of these pathogens. "
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    ABSTRACT: Ticks are important vector arthropods of human and animal pathogens. As information about agents of disease circulating in vectors in Portugal is limited, the aim of the present study was to detect bacteria and parasites with veterinary and zoonotic importance in ticks collected from dogs, cats, and field vegetation. A total of 925 ticks, comprising 888 (96.0%) adults, 8 (0.9%) nymphs, and 29 (3.1%) larvae, were collected in 4 geographic areas (districts) of Portugal. Among those, 620 (67.0%) were removed from naturally infested dogs, 42 (4.5%) from cats, and 263 (28.4%) were questing ticks obtained from field vegetation. Rhipicephalus sanguineus was the predominant tick species, and the only one collected from dogs and vegetation, while all Ixodes ricinus specimens (n = 6) were recovered from cats. Rickettsia massiliae and Rickettsia conorii were identified in 35 ticks collected from cats and dogs and in 3 ticks collected from dogs. Among ticks collected from cats or dogs, 4 Rh. sanguineus specimens were detected with Hepatozoon felis, 3 with Anaplasma platys, 2 with Hepatozoon canis, one with Anaplasma phagocytophilum, one with Babesia vogeli, one with Borrelia burgdorferi sensu lato and one with Cercopithifilaria spp. Rickettsia helvetica was detected in one I. ricinus tick collected from a cat. To the best of our knowledge, this was the first time that Cercopithifilaria spp., Ba. vogeli, H. canis, and H. felis have been detected in ticks from Portugal. The wide range of tick-borne pathogens identified, some of zoonotic concern, suggests a risk for the emergence of tick-borne diseases in domestic animals and humans in Portugal. Further studies on these and other tick-borne agents should be performed to better understand their epidemiological and clinical importance, and to support the implementation of effective control measures.
    Ticks and Tick-borne Diseases 06/2014; 5(4). DOI:10.1016/j.ttbdis.2014.01.009 · 2.72 Impact Factor
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