Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn

Uppsala University Hospital, Uppsala, Uppsala, Sweden
New England Journal of Medicine (Impact Factor: 54.42). 06/2006; 354(20):2188-90; author reply 2188-90.
Source: PubMed

ABSTRACT ABSTRACT Background Persistent pulmonary,hypertension of the newborn,(PPHN) is associated with sub- stantial infant mortality and morbidity. A previous cohort study suggested a pos- sible association between maternal use of the selective serotonin-reuptake inhibitor (SSRI) fluoxetine late in the third trimester of pregnancy and the risk of PPHN in the infant. Weperformed,a case–control study to assess whether PPHN is associated with exposure to SSRIs during late pregnancy. Methods

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