Laryngeal metastasis from sigmoid colon adenocarcinoma followed by peristomal recurrence
Department of Otolaryngology, Head and Neck Surgery, Section of Anatomic Pathology, University of Padova, Padova, Italy.Acta Oto-Laryngologica (Impact Factor: 1.1). 06/2006; 126(6):661-3. DOI: 10.1080/00016480500452590
Considering clinical evidence,<2% of laryngeal malignancies are distant metastases. Cutaneous melanomas are the preponderant primaries metastasizing to the larynx, followed by renal cell carcinomas, breast and lung carcinomas. Colonic adenocarcinoma metastases to the larynx are extremely rare: only 13 cases have been described since 1972. We present the first case of sigmoid colon adenocarcinoma metastasis to the larynx in a patient who developed peristomal malignancy recurrence after total laryngectomy. Patients with metastasis of colonic adenocarcinoma to the larynx usually present with disseminated disease: in view of the poor chances of long-term survival of these patients conservative palliative laryngeal treatments should be carried out to improve the quality of life. Curative treatment should be considered only in isolated laryngeal metastasis.
- Acta Oto-Laryngologica 12/2007; 127(11):1231-2. DOI:10.1080/00016480601089440 · 1.10 Impact Factor
- Otolaryngology Head and Neck Surgery 06/2010; 142(6):911-2. DOI:10.1016/j.otohns.2010.01.007 · 2.02 Impact Factor
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ABSTRACT: Malignancies metastatic to the larynx are rare, accounting for fewer than 1% of all laryngeal cancers with metastatic sources; the most common of these metastases are cutaneous melanomas and renal cell carcinomas. Only 13 cases of colon cancer and 2 cases of rectal adenocarcinoma metastatic to the larynx have been previously reported in the literature. We report a new case of rectal adenocarcinoma metastatic to the larynx that resulted in subglottic stenosis in a 60-year-old man. We also review the literature, and we discuss the presentations of and treatments for this rare entity.Ear, nose, & throat journal 04/2011; 90(4):E28. · 1.00 Impact Factor
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