Laryngeal metastasis from sigmoid colon adenocarcinoma followed by peristomal recurrence

Department of Otolaryngology, Head and Neck Surgery, Section of Anatomic Pathology, University of Padova, Padova, Italy.
Acta Oto-Laryngologica (Impact Factor: 0.99). 06/2006; 126(6):661-3. DOI: 10.1080/00016480500452590
Source: PubMed

ABSTRACT Considering clinical evidence,<2% of laryngeal malignancies are distant metastases. Cutaneous melanomas are the preponderant primaries metastasizing to the larynx, followed by renal cell carcinomas, breast and lung carcinomas. Colonic adenocarcinoma metastases to the larynx are extremely rare: only 13 cases have been described since 1972. We present the first case of sigmoid colon adenocarcinoma metastasis to the larynx in a patient who developed peristomal malignancy recurrence after total laryngectomy. Patients with metastasis of colonic adenocarcinoma to the larynx usually present with disseminated disease: in view of the poor chances of long-term survival of these patients conservative palliative laryngeal treatments should be carried out to improve the quality of life. Curative treatment should be considered only in isolated laryngeal metastasis.

1 Follower
  • [Show abstract] [Hide abstract]
    ABSTRACT: We present a case of adenocarcinoma of colon with unusual metastasis to inguinal lymph nodes. Our patient is a young male with bilateral inguinal lymphadenopathy, bone pains, and jaundice who presented as carcinoma of unknown primary. He was diagnosed as widely metastatic adenocarcinoma of colon for which he received chemotherapy and has had a good response to the treatment.
    Indian journal of medical and paediatric oncology 07/2011; 32(3):168-70. DOI:10.4103/0971-5851.92822
  • [Show abstract] [Hide abstract]
    ABSTRACT: The temporary tracheostoma's metastases of head and neck cancer had already been reported in the literature. So far, they had been considered as regional dissemination of the malignant disease. We report a case of temporary tracheostoma's metastasis of carcinoma from non-head-and-neck primary site, what has not been reported in the literature, yet. Therefore, it is the first reported case of the systemic dissemination of malignant tumour into temporary tracheostoma. Fifty-four-year-old female patient, previously treated for a rectal adenocarcinoma, reported in our office with exophytic pink tissue masses around the temporary tracheostoma. The biopsy and immunohistochemistry findings were consistent with temporary tracheostoma's metastasis of the rectal adenocarcinoma. The patient received palliative radiotherapy and died of systemic progression of the disease. The patients with history of primary cancer of any origin and exophytic proliferating changes around the tracheostoma require an appropriate diagnostic work-up including a biopsy. The type of treatment depends on the extent of the disease, previous therapy and general condition of the patient.
    Radiology and Oncology 12/2014; 48(4):393-396. DOI:10.2478/raon-2013-0079 · 1.60 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Metastasis of colorectal adenocarcinoma to the larynx is a very rare condition. Here, we report a 72-year-old woman with a history of rectal adenocarcinoma. She was referred for whole-body FDG PET/CT scanning because of an elevating serum level of carcinoembryonic antigen. PET images showed focally increased FDG accumulation in the larynx (SUVmax=12.9). Coregistered CT images showed mild wall thickening at the left subglottic area. The findings of after excisional biopsy confirmed that this FDG-avid lesion was metastatic adenocarcinoma of the colorectal origin.
    Clinical nuclear medicine 07/2012; 37(7):e178-80. DOI:10.1097/RLU.0b013e3182443b98 · 2.86 Impact Factor