Article

Burke, W. & Press, N. Genetics as a tool to improve cancer outcomes: ethics and policy. Nature Rev. Cancer 6, 476-482

Department of Medical History and Ethics, University of Washington, BOX 357120, 1959 North East Pacific, Room A204, Seattle, Washington 98195-7120, USA.
Nature reviews. Cancer (Impact Factor: 37.91). 07/2006; 6(6):476-82. DOI: 10.1038/nrc1890
Source: PubMed

ABSTRACT Genetic research is rapidly increasing the opportunities for the detection of inherited cancer risk. Clinicians and policy makers must ensure the adequate evaluation of the benefits and harms of this new area of practice, address the challenges of family-based detection of individuals at risk and develop practice guidelines and educational strategies that are responsive to rapidly changing knowledge. When the benefits of testing are well established, efforts must also be made to ensure access to genetic services for all who can benefit.

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    • "These findings highlight the importance of evaluating participant willingness a priori to receive such information and discussing implications of results. Several authors (Bookman et al., 2006; Burke and Press, 2006) have drafted guidelines regarding the selection of individuals for genetic testing and a program of individualized assessments to discuss testing and dissemination. Our study, which assessed the opinions of a subset of individuals from the Seattle C-CFR, was conducted as an initial step in this process of disclosure for participants enrolled in the cancer registry. "
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