Smoking cessation

Respiratory Unit, Aberdeen Royal Infirmary, Aberdeen.
BMJ (online) (Impact Factor: 17.45). 07/2006; 332(7553):1324-6. DOI: 10.1136/bmj.332.7553.1324
Source: PubMed
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    • "Secondary prevention remains an important focus. Brief advice is a cost-effective way of encouraging smoking cessation but the quit rate after any given contact is relatively low (Srivastava et al., 2006). COPD patients who smoke appear to be relatively resistant to other treatments, possibly reflecting the fact that the most susceptible will have quit already before they enter a study. "
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    ABSTRACT: Chronic obstructive pulmonary disease (COPD) is now recognized as a major source of ill health around the world with an important impact on both developed and developing economies. The emphasis in research has shifted from a purely physiological focus that mainly considered how airway smooth muscle tone can be modulated to improve lung emptying. Although long-acting inhaled beta-agonist and antimuscarinic antagonists have improved clinical management for many symptomatic patents, there is increasing attention being paid to the inflammatory component of COPD in the airways and lung parenchyma and to its close association with other diseases, which cannot simply be attributed to their having a common risk factor such as tobacco smoking. This clinical review is intended to identify not only those areas where pharmacological treatment has been successful or has offered particular insights into COPD but also to consider where existing treatment is falling short and new opportunities exist to conduct original investigations. A picture of considerable complexity emerges with a range of clinical patterns leading to several common end points such as exacerbations, exercise impairment and mortality. Defining subsets of patients responsive to more specific interventions is the major challenge for the next decade in this field.
    British Journal of Pharmacology 10/2008; 155(4):487-93. DOI:10.1038/bjp.2008.362 · 4.84 Impact Factor
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    • "The treatments for smoking cessation include behavioral support, nicotine replacement therapy, bupropion and other drug treatments (4). However, stopping smoking is difficult, mainly due to nicotine withdrawal symptoms (NWS). "
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    ABSTRACT: This study evaluated whether improvements in nicotine withdrawal symptoms (NWS), depression and anxiety are greater for body acupuncture than for sham acupuncture. Smoking volunteers from the public were randomized to receive six sessions of either real or sham acupuncture for 2 weeks. The primary outcome measure was NWS measured by the Minnesota Nicotine Withdrawal Score, and the secondary measures were scores on the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). Eighty volunteers were randomized into real acupuncture (n = 38) and sham acupuncture (n = 42) groups, of which 46 subjects (22 and 24 in the real and sham acupuncture groups, respectively) completed the treatment and the 2-week follow-up. An intention-to-treat analysis revealed that the NWS did not differ significantly between the real and sham acupuncture groups immediately after the treatment (12.2 ± 9.7 and 12.8 ± 7.7, respectively; mean ± SD) and at the 2-week follow-up (11.7 ± 10.2 and 12.6 ± 7.8). Both groups also showed similar improvements in BDI and BAI scores. These results indicate that the real acupuncture treatment tested in this trial was no more effective than sham acupuncture at reducing NWS, depression and anxiety for smoking cessation.
    Evidence-based Complementary and Alternative Medicine 08/2008; 7(2):233-8. DOI:10.1093/ecam/nem179 · 1.88 Impact Factor
  • Salud publica de Mexico 01/2007; DOI:10.1590/S0036-36342007000800003 · 0.94 Impact Factor
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