Effect of fluoride toothpastes on enamel demineralization

Faculty of Dental Medicine, University of Witten/Herdecke, Witten, Germany.
BMC Oral Health (Impact Factor: 1.15). 02/2006; 6:8. DOI: 10.1186/1472-6831-6-8
Source: PubMed

ABSTRACT It was the aim of this study to investigate the effect of four different toothpastes with differing fluoride compounds on enamel remineralization.
A 3 x 3 mm window on the enamel surface of 90 human premolars was demineralized in a hydroxyethylcellulose solution at pH 4.8. The teeth were divided into 6 groups and the lower half of the window was covered with varnish serving as control. The teeth were immersed in a toothpaste slurry containing: placebo tooth paste (group 1); remineralization solution (group 2); Elmex Anticaries (group 3); Elmex Sensitive (group 4); Blend-a-med Complete (group 5) and Colgate GRF (group 6). Ten teeth of each group were used for the determination of the F- content in the superficial enamel layer and acid solubility of enamel expressed in soluble phosphorus. Of 6 teeth of each group serial sections were cut and investigated with polarization light microscopy (PLM) and quantitative energy dispersive X-ray analysis (EDX).
The PLM results showed an increased remineralization of the lesion body in the Elmex Anticaries, Elmex Sensitive and Colgate GRF group but not in the Blend-a-med group. A statistically significant higher Ca content was found in the Elmex Anticaries group. The fluoride content in the superficial enamel layer was significantly increased in both Elmex groups and the Blend-a-med group. Phosphorus solubility was significantly decreased in both Elmex groups and the Blend-a-med group.
It can be concluded that amine fluoride compounds in toothpastes result in a clearly marked remineralization of caries like enamel lesions followed by sodium fluoride and sodium monofluorophosphate formulations.

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    ABSTRACT: Objective: To identify the different fluoride levels and compounds in locally manufactured tooth pastes and the dental caries status of Karachi, Pakistan. Cross-Sectional Study. This study was conducted in the Dental Out Patient Department (OPD) of a public sector tertiary care hospital, over a period of 15 days. The local brands of toothpastes available were collected through the market survey of a major departmental store of Karachi. The quantity and the compound of fluoride claimed by the manufacturer were recorded. A group of 300 patients were evaluated through a structured proforma for their demographic characteristics, brand name of the tooth paste which they claimed to use for the past six months and the number of decayed teeth (by type 1 dental examination). Results: The clinical dental examination revealed that active tooth decay of 32.33%, 15.33% and 52.33% was observed in subjects reported the use of tooth paste with 1000ppm, 1400ppm and those which did not claim any fluoride concentration, respectively. Decay count of 52.66% was identified in subjects who used tooth pastes with sodium fluoride, while it was 37.33% where sodium mono fluoro phosphate was present. Conclusion: Relative caries preventive effects of fluoride toothpastes increase with increase in fluoride levels. NaF has been found to be superior to SMFP for the control of dental caries.
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    ABSTRACT: Presence of available and stable fluoride in a dentifrice formulation is a major requirement for an anti-caries effect. Although the available fluoride concentration in Iranian dentifrices has been reported in previous studies, there is little information on its stability; which is dependent upon dentifrice formulation. This study was done to assess the fluoride ion concentration and stability in four widely used dentifrices in Iran. In this analytical study, three samples of each brand of dentifrice (Nasim, Pooneh, Crest, and Signal) were purchased. Total fluoride (TF) and total soluble fluoride (TSF) concentrations were determined by ion specific electrodes. Data about TF were analyzed by one-way analysis of variance (ANOVA). Kruskal-Wallis and Mann-Whitney tests were used for nonparametric data (TSF). All dentifrices had more than 1000 ppm of fluoride ions. TSF in Crest was significantly higher than in other dentifrices (P<0.0001) and was over the maximum permitted dose. The TF concentration in Iranian toothpastes was sufficient to prevent caries.
    09/2014; 11(5):604-9.

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