Article

Evaluation of intracranial meningioma resection with a surgical aspirator in dogs: 17 cases (1996-2004).

Department of Surgery, The Animal Medical Center, 510 E 62nd St, New York, NY 10021, USA.
Journal of the American Veterinary Medical Association (Impact Factor: 1.72). 08/2006; 229(3):394-400. DOI: 10.2460/javma.229.3.394
Source: PubMed

ABSTRACT To determine results of intracranial meningioma resection by use of a surgical aspirator and assess prognostic factors associated with intracranial meningiomas in dogs.
Retrospective case series.
17 dogs.
Medical records of dogs that underwent resection of an intracranial meningioma by use of a surgical aspirator were reviewed. Information pertaining to signalment, imaging findings, clinical signs, duration of clinical signs, preoperative treatment, location of the tumor, results of histologic assessment, outcome, and necropsy results was obtained from the medical record. Clients and referring veterinarians were contacted via telephone for information on recurrence of clinical signs and postoperative survival time.
16 dogs were > 7 years of age, and all 17 dogs had seizures before surgery. The most commonly affected breed was the Golden Retriever, represented by 6 of the 17 dogs. Median survival time was 1,254 days. Of the data collected, only histologic subtype of the tumor was prognostic. Analysis of survival times according to histologic tumor subtypes indicated that the order from most brief to longest was as follows: anaplastic, 0 days; fibroblastic, 10 days; psammomatous, > 313 days; meningothelial, > 523 days; and transitional, 1,254 days.
Use of a surgical aspirator to resect intracranial meningiomas in dogs was associated with longer survival times than those achieved with traditional surgery alone or traditional surgery combined with radiation therapy. Dogs with meningothelial, psammomatous, or transitional intracranial meningioma subtypes appeared to have a better prognosis than dogs with other subtypes of meningioma.

0 Bookmarks
 · 
49 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To report the effectiveness of MRI scanning during brain meningioma resection surgery in canine and feline. Twenty three cases from 2006 to 2008 in canine and feline diagnosed with meningioma. All were aged between 8 years and 16 years old. There were 12 males and 11 females. Appropriate craniotomy was performed for each case according to the initial MRI taken to diagnose meningioma prior to the surgery. Once dura mater was exposed, an MRI biopsy needle was placed in the tumor as a guide. 1st MRI during the surgery was scanned with this needle to confirm the location of the tumor. This MRI image was also processed and displayed by MPR to reveal the tumor extent in three dimensions. Sonopet was applied in the middle of the tumor to destroy the inner part and release pressure from the entire tumor. Creating some space between the brain tissue and tumor, we treated blood vessels and carefully resected them. This procedure was repeated until complete removal of the tumor was confirmed by MRI. Sixteen of the twenty three cases survived for more than 2 years postoperatively. The other seven died due to other disorders within 2 years. Our method with MRI navigation during the surgery improved our surgical performance and contributed to a prolonged survival time for the patients. In order to perform multiple MRI procedures smoothly during the surgery, it is necessary to have skillful assistants.
    Journal of Veterinary Medical Science 11/2013; · 0.88 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Stereotactic radiosurgery (SRS) is a procedure that delivers a single large radiation dose to a well-defined target. Here, we describe a frameless SRS technique suitable for intracranial targets in canines. Medical records of dogs diagnosed with a primary intracranial tumour by imaging or histopathology that underwent SRS were retrospectively reviewed. Frameless SRS was used successfully to treat tumours in 51 dogs with a variety of head sizes and shapes. Tumours diagnosed included 38 meningiomas, 4 pituitary tumours, 4 trigeminal nerve tumours, 3 gliomas, 1 histiocytic sarcoma and 1 choroid plexus tumour. Median survival time was 399 days for all tumours and for dogs with meningiomas; cause-specific survival was 493 days for both cohorts. Acute grade III central nervous system toxicity (altered mentation) occurred in two dogs. Frameless SRS resulted in survival times comparable to conventional radiation therapy, but with fewer acute adverse effects and only a single anaesthetic episode required for therapy.
    Veterinary and Comparative Oncology 09/2013; · 1.56 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Intracranial neoplasia is a common clinical condition in domestic companion animals, particularly in dogs. Application of advances in standard diagnostic and therapeutic modalities together with a broad interest in the development of novel translational therapeutic strategies in dogs has resulted in clinically relevant improvements in outcome for many canine patients. This review highlights the status of current diagnostic and therapeutic approaches to intracranial neoplasia and areas of novel treatment currently in development.
    Journal of Veterinary Internal Medicine 05/2014; · 2.06 Impact Factor