Evaluation of intracranial meningioma resection with a surgical aspirator in dogs: 17 Cases (1996-2004)
ABSTRACT To determine results of intracranial meningioma resection by use of a surgical aspirator and assess prognostic factors associated with intracranial meningiomas in dogs.
Retrospective case series.
Medical records of dogs that underwent resection of an intracranial meningioma by use of a surgical aspirator were reviewed. Information pertaining to signalment, imaging findings, clinical signs, duration of clinical signs, preoperative treatment, location of the tumor, results of histologic assessment, outcome, and necropsy results was obtained from the medical record. Clients and referring veterinarians were contacted via telephone for information on recurrence of clinical signs and postoperative survival time.
16 dogs were > 7 years of age, and all 17 dogs had seizures before surgery. The most commonly affected breed was the Golden Retriever, represented by 6 of the 17 dogs. Median survival time was 1,254 days. Of the data collected, only histologic subtype of the tumor was prognostic. Analysis of survival times according to histologic tumor subtypes indicated that the order from most brief to longest was as follows: anaplastic, 0 days; fibroblastic, 10 days; psammomatous, > 313 days; meningothelial, > 523 days; and transitional, 1,254 days.
Use of a surgical aspirator to resect intracranial meningiomas in dogs was associated with longer survival times than those achieved with traditional surgery alone or traditional surgery combined with radiation therapy. Dogs with meningothelial, psammomatous, or transitional intracranial meningioma subtypes appeared to have a better prognosis than dogs with other subtypes of meningioma.
- SourceAvailable from: Rafał Sapierzyński
Conference Paper: GGMAC-based equalizer for nonlinear channels[Show abstract] [Hide abstract]
ABSTRACT: This paper deals with the compensation for the nonlinear distortion introduced by power-efficient amplifiers on linear modulation by means of equalization. We propose a new equalizer based on a reduced-complexity network called the generalized cerebellar model arithmetic computer (GMAC) GCMAC. The GCMAC-based equalizer is compared with other well-known structures such as the Volterra filter and the multi-layer perceptron. Extensive computer simulations have been carried out. The obtained results show the effectiveness of the proposed structure to compensate for strong nonlinearitiesAcoustics, Speech and Signal Processing, 1998. Proceedings of the 1998 IEEE International Conference on; 06/1998
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ABSTRACT: Intracranial meningiomas are the most common primary brain tumors in dogs. Classification of meningiomas by tumor grade and subtype has not been reported, and the value of magnetic resonance imaging (MRI) characteristics for predicting tumor subtype and grade has not been investigated. Canine intracranial meningiomas are a heterogenous group of tumors with differing histological subtypes and grades. Prediction of histopathological classification is possible based on MRI characteristics. One hundred and twelve dogs with a histological diagnosis of intracranial meningioma. Retrospective observational study. Meningiomas were overrepresented in the Golden Retriever and Boxer breeds with no sex predilection. The incidence of specific tumor grades was 56% benign (Grade I), 43% atypical (Grade II), and 1% malignant (Grade III). Grade I histological subtypes included meningothelial (43%), transitional (40%), microcystic (8%), psammomatous (6%), and angiomatous (3%). No statistically significant (P < .05) associations were found among tumor subtype or grade and any of the MRI features studied. Meningiomas in dogs differ from their counterparts in humans mainly in their higher incidence of atypical (Grade II) tumors observed. MRI characteristics do not allow for prediction of meningioma subtype or grade, emphasizing the necessity of histopathology for antemortem diagnosis. The higher incidence of atypical tumors in dogs may contribute to the poorer therapeutic response in dogs with meningiomas as compared with the response in humans with meningiomas.Journal of Veterinary Internal Medicine 07/2008; 22(3):586-95. DOI:10.1111/j.1939-1676.2008.00042.x · 2.22 Impact Factor