Article

Preoperative Corticosteroid Oral Therapy and Intraoperative Bleeding during Functional Endoscopic Sinus Surgery in Patients with Severe Nasal Polyposis: A Preliminary Investigation

Department of Otolaryngology, Medical University of Bialystok, Bialystok, Poland.
The Annals of otology, rhinology, and laryngology (Impact Factor: 1.05). 08/2006; 115(7):490-4. DOI: 10.1177/000348940611500702
Source: PubMed

ABSTRACT The aim of the study was to investigate whether orally administered steroids might improve surgical field conditions during functional endoscopic sinus surgery.
Total blood loss and visualization of the surgical field during the surgical procedure were compared in 2 groups of 18 patients each with severe nasal polyposis. The groups were similar in respect to age, body mass index, general health status, incidence of allergy, bronchial asthma, aspirin triad, and stage of disease. One group received 30 mg of prednisone daily for 5 consecutive days before the operation. The second group served as a control.
Although the total blood loss was only slightly less in the steroid group, the visual conditions of the surgical field improved significantly.
Better surgical field conditions were the results of the powerful anti-inflammatory and antiedematous activity of the drug, which facilitated blood and secretion evacuation from the operated area and prevented the optic system from staining.

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    • "Pre-operative steroid administration in cases of severe nasal polyposis improves visibility due to its anti-inflammatory and anti-edematous effect.[11] Topical vasoconstrictors are applied to decrease blood loss and mucosal congestion, but hypertension and tachycardia may occur,[12] controlled hypotension is commonly used to achieve blood less operative field.[13] "
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