Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents.

Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.
Bioorganic & Medicinal Chemistry Letters (Impact Factor: 2.34). 11/2006; 16(20):5392-7. DOI: 10.1016/j.bmcl.2006.07.064
Source: PubMed

ABSTRACT We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.

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