The histopathologic effects of balloon dacryoplasty on the rabbit nasolacrimal duct
ABSTRACT To examine the histopathologic effects of balloon dacryoplasty on the nasolacrimal duct of the rabbit.
Sixteen nasolacrimal ducts of 8 infant white New Zealand rabbits were divided into 3 treatment groups: a control group, a 2 mm balloon dilation group, and a 3 mm balloon dilation group. The LacriCath balloon catheter (Quest, Medical, Allen, TX) was used for nasolacrimal duct dilation according to the manufacturer's recommended human protocol. The rabbits were euthanized at 1, 3, and 7 days after treatment and the nasolacrimal ducts were harvested for histological examination.
There were no significant differences between treatment groups in the number of neutrophils in the lumen, epithelium, and stroma of the duct; the number of monocytes in the stroma of the duct; or in the number of red blood cells in the stroma of the duct. No differences were found in overall cellularity of any type in the nasolacrimal ducts of treated and untreated rabbits. Finally, no histopathologic signs of crush injury were evident.
Balloon dacryoplasty does not induce significant inflammation or crush injury in the nasolacrimal duct of a rabbit model.
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ABSTRACT: Congenital lachrymal obstruction is a frequent motive of consultation. Endoscopic control in the inferior meatus of the nostril allows to realize surgical controlled procedures. The aim of the study is to analyze the result obtained in the treatment of congenital obstruction of the lachrymal duct by monocanalicular intubation with Monoka and endoscopic control in children who had failed two lachrymal system probings. Between October 2004 and September 2008 this technique was performed in a prospective study on 36 patients with congenital nasolacrimal obstruction who had failed two lachrymal system probings. The mean age was 36.2 months (range 12-66 months). Patients were followed at 6 weeks, 3 months and 6 months, with clinical evaluation by Munk's score and ophthalmologic exam using dye disappearance test. Success was defined as complete resolution of signs and symptoms (Munk 0) and no fluorescein remaining in dye disappearance test (grade 0). The procedure was successful in 91.66% of the cases and acceptable in 8.33%. We have not found any complication or side effects, and not further procedures have been needed on any patient. Balloon dachryoplasty with monocanalicular intubation under endoscopic control is a safe, easy to perform and effective surgical technique for the treatment of congenital lachrymal obstruction with two previous failed lachrymal system probings.Acta Otorrinolaringológica Española 11/2009; 60(6):409-14. DOI:10.1016/j.otorri.2009.06.006
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ABSTRACT: To compare the success rate of balloon catheter dilatation of the nasolacrimal duct with probing and irrigation as primary treatment for congenital dacryostenosis. Charts of all children who were operated on for the first time for congenital dacryostenosis during the years 2004 to 2006 were analysed and the outcomes compared. Surgical success was defined as absence of epiphora and mucous discharge, and of increased tear lake, at the last visit. 68 children (114 eyes) underwent balloon catheter dilatation and 37 children (60 eyes) had probing. Children who had balloon dilatation were significantly older: mean age 55.98±113.6 (range 9.0-728.0) months as opposed to 18.5±6.5 (range 7.0-60.0) months, p<0.01). After a mean follow-up time of 15.4 (range 4-32) months, 102 of 114 eyes were defined as successfully treated following balloon catheter dilatation (89.5% success rate) compared with 52 of 60 eyes following probing (86.7% success rate, p=0.581). Five of six patients (80%) in which the #00 probe could only hardly be inserted into the nasolacrimal duct because of firm bone resistance failed in the probing group, as opposed to only 2/10 (20%) in the balloon catheter group (p=0.03). Children who had balloon catheter dilatation had a slightly better success rate than those who had probing; however, this difference was statistically significant only for patients who had a relatively narrow nasolacrimal bone duct.The British journal of ophthalmology 10/2010; 95(5):634-6. DOI:10.1136/bjo.2010.183301 · 2.81 Impact Factor