The histopathologic effects of balloon dacryoplasty on the rabbit nasolacrimal duct
ABSTRACT To examine the histopathologic effects of balloon dacryoplasty on the nasolacrimal duct of the rabbit.
Sixteen nasolacrimal ducts of 8 infant white New Zealand rabbits were divided into 3 treatment groups: a control group, a 2 mm balloon dilation group, and a 3 mm balloon dilation group. The LacriCath balloon catheter (Quest, Medical, Allen, TX) was used for nasolacrimal duct dilation according to the manufacturer's recommended human protocol. The rabbits were euthanized at 1, 3, and 7 days after treatment and the nasolacrimal ducts were harvested for histological examination.
There were no significant differences between treatment groups in the number of neutrophils in the lumen, epithelium, and stroma of the duct; the number of monocytes in the stroma of the duct; or in the number of red blood cells in the stroma of the duct. No differences were found in overall cellularity of any type in the nasolacrimal ducts of treated and untreated rabbits. Finally, no histopathologic signs of crush injury were evident.
Balloon dacryoplasty does not induce significant inflammation or crush injury in the nasolacrimal duct of a rabbit model.
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ABSTRACT: To compare the success rate of balloon catheter dilatation of the nasolacrimal duct with probing and irrigation as primary treatment for congenital dacryostenosis. Charts of all children who were operated on for the first time for congenital dacryostenosis during the years 2004 to 2006 were analysed and the outcomes compared. Surgical success was defined as absence of epiphora and mucous discharge, and of increased tear lake, at the last visit. 68 children (114 eyes) underwent balloon catheter dilatation and 37 children (60 eyes) had probing. Children who had balloon dilatation were significantly older: mean age 55.98±113.6 (range 9.0-728.0) months as opposed to 18.5±6.5 (range 7.0-60.0) months, p<0.01). After a mean follow-up time of 15.4 (range 4-32) months, 102 of 114 eyes were defined as successfully treated following balloon catheter dilatation (89.5% success rate) compared with 52 of 60 eyes following probing (86.7% success rate, p=0.581). Five of six patients (80%) in which the #00 probe could only hardly be inserted into the nasolacrimal duct because of firm bone resistance failed in the probing group, as opposed to only 2/10 (20%) in the balloon catheter group (p=0.03). Children who had balloon catheter dilatation had a slightly better success rate than those who had probing; however, this difference was statistically significant only for patients who had a relatively narrow nasolacrimal bone duct.The British journal of ophthalmology 10/2010; 95(5):634-6. DOI:10.1136/bjo.2010.183301 · 2.81 Impact Factor
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