Article

Symmetry breaking in C. elegans: another gift from the sperm.

Biology Department, The University of North Carolina at Chapel Hill, 27599, USA.
Developmental Cell (Impact Factor: 12.86). 10/2006; 11(3):273-4. DOI: 10.1016/j.devcel.2006.08.007
Source: PubMed

ABSTRACT Polarization of the C. elegans embryo depends on the sperm-contributed centrosome, which cues a retraction of the actomyosin cortex to the opposite end of the embryo by an unknown mechanism. New evidence reveals that the sperm donates a second polarizing cue that may locally relax the actomyosin cortex near the point of sperm entry.

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