The toxicity of cadmium and resulting hazards for human health. J Occup Med Toxicol 1:22

Department for Paediatric Pneumology and Immunology, Charité-School of Medicine, Free University and Humboldt University of Berlin, Germany.
Journal of Occupational Medicine and Toxicology (Impact Factor: 1.62). 02/2006; 1(1):22. DOI: 10.1186/1745-6673-1-22
Source: PubMed

ABSTRACT Cadmium (Cd) has been in industrial use for a long period of time. Its serious toxicity moved into scientific focus during the middle of the last century. In this review, we discuss historic and recent developments of toxicological and epidemiological questions, including exposition sources, resorption pathways and organ damage processes.

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    • "Heavy metals can lead to adverse health effects on animals and humans due to their toxicity (Dong et al. 2010; EI Hamiani et al. 2010; Raju 2012). High Mn content in the human body can cause skeletal abnormalities and brain damage (Kalembkiewicz et al. 2008), and Cd exposure can increase the chance of renal tubular damage, osteoporosis and cancer (Järup et al. 1998; Godt et al. 2006). The contamination of road soil by vehicular emission and dust is a major source of dumping soil contamination . "
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    ABSTRACT: This study assessed soil pollution in the Varanasi environs of Uttar Pradesh in India. Assessing the concentration of potentially harmful heavy metals in the soils is imperative in order to evaluate the potential risks to human. To identify the concentration and sources of heavy metals and assess the soil environmental quality, 23 samples were collected from different locations covering dumping, road and agricultural area. The average concentrations of the heavy metals were all below the permissible limits according to soil quality guidelines except Cu (copper) and Pb (lead) in dumping and road soils. Soil heavy metal contamination was assessed on the basis of geoaccumulation index (Igeo), pollution index (PI) and integrated pollution index (IPI). The IPI of the metals ranged from 0.59 to 9.94, with the highest IPI observed in the dumping and road soils. A very significant correlation was found between Pb and Cu. The result of principal component analysis suggested that PC1 was mainly affected by the use of agrochemicals, PC2 was affected by vehicular emission and PC3 was affected by dumping waste. Meanwhile, PC4 was mainly controlled by parent material along with anthropogenic activities. Appropriate measures should be taken to minimize the heavy metal levels in soils and thus protect human health.
    Environmental Monitoring and Assessment 06/2015; 187(6):4577. DOI:10.1007/s10661-015-4577-4 · 1.68 Impact Factor
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    • "Currently, aquatic ecosystems have been severely contaminated by heavy metal ions discharged from electrochemical industry and other industrial sectors, which not only affect biodiversity, but also cause toxic effect on human being through the food chain accumulation [1]. It has been well documented that Cd 2+ can result in extensive toxic effect on cell physiology by disrupting enzymatic functions through its binding to the functional groups or replacing other metal ions therein [2]. Although Zn 2+ is a micronutrient for cell growth and metabolism that regulates gene expression through the role of zinc fingers or acting as a cofactor for many metalloenzymes , it is also toxic at high concentrations [3] [4]. "
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    ABSTRACT: Microalgae are attracting attention due to their potentials in mitigating CO2 emissions and removing environmental pollutants. However, harvesting microalgal biomass from diluted cultures is one of the bottlenecks for developing economically viable processes for this purpose. Microalgal cells can be harvested by cost-effective sedimentation when flocculating strains are used. In this study, the removal of Zn2+ and Cd2+ by the flocculating Chlorella vulgaris JSC-7 was studied. The experimental results indicated that more than 80% Zn2+ and 60% Cd2+ were removed by the microalgal culture within 3 days in the presence up to 20.0 mg/L Zn2+ and 4.0 mg/L Cd2+, respectively, which were much higher than that observed with the culture of the non-flocculating C. vulgaris CNW11. Furthermore, the mechanism underlying this phenomenon was explored by investigating the effect of Zn2+ and Cd2+ on the growth and metabolic activities of the microalgal strains. It was found that the flocculation of the microalga improved its growth, synthesis of photosynthetic pigments and antioxidation activity under the stressful conditions, indicating a better tolerance to the heavy metal ions for a potential in removing them more efficiently from contaminated wastewaters, together with a bioremediation of other nutritional components contributed to the eutrophication of aquatic ecosystems.
    Journal of Hazardous Materials 05/2015; 289:38-45. · 4.53 Impact Factor
    • "In 1817, Friedrich Stromeyer first time highlighted the kidney, bone and pulmonary damages by cadmium toxicity in human [2]. "
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