Is cardiorespiratory fitness related to quality of life in survivors of breast cancer?

European University of Madrid, Madrid, Spain.
The Journal of Strength and Conditioning Research (Impact Factor: 1.86). 09/2006; 20(3):535-40. DOI: 10.1519/00124278-200608000-00013
Source: PubMed

ABSTRACT The purpose of this study was to investigate whether indices of cardiorespiratory fitness are related to quality of life (QOL) in women survivors of breast cancer. Using the European Organization for Research and Treatment of Cancer QLQ-30 questionnaire, we assessed the QOL of 16 participants (age, 50 +/- 9 years; body mass, 66.6 +/- 9.6 kg). All participants performed incremental cycle ergometer exercise to determine several indices of cardiorespiratory fitness (e.g., peak oxygen uptake [.V(O2)peak, in L.min(-1),]), peak power output (PPO, in W), PPO/ body mass (, peak heart rate (HRpeak, b.min(-1), peak ventilation (VEpeak), and .V(O2) and heart rate (HR) at the ventilatory (VT) and respiratory compensation (RCT) thresholds. Relationships between QOL and variables were assessed using Spearman rank-difference correlation tests. A significant inverse relationship (p < 0.05) was found for QOL scores and values for age (years) and body mass (kg) ( = -0.53), %HRpeak@VT ( = -0.59) and %VEpeak@VT ( = -0.61). A significant positive relationship (p < 0.05) was found for QOL and PPO/body mass ( = 0.59) and HRpeak ( = 0.78), .V(O2)@RCT ( ( = 0.51), power output (PO, expressed as either W or at RCT, and HR at RCT ( = 0.54). No other significant relationship was found between QOL and variables obtained from the tests. In conclusion, these findings highlight possible relationships between cardiorespiratory fitness and well-being in survivors of breast cancer. From a practical point of view, our data emphasize the need for this population to engage in programmed cardiorespiratory exercise training, mainly designed to improve VT and RCT. The improvement of both submaximal indices can have a beneficial effect on QOL.

Download full-text


Available from: Fernando Herrero, Apr 18, 2014
  • Source
    • "In the current study, the average of maximal oxygen consumption, VO 2peak , attained during the cardiorespiratory endurance test was 5.81 ± 1.26 METs for all the survivors (CATotal). These results were similar to previous studies (Cheema & Gaul, 2006; Courneya et al., 2003; Fairey et al., 2005; Herrero et al., 2006; L. W. Jones et al., 2007); however, other studies have included survivors with other comorbidities in addition to controlled hypertension (Courneya et al., 2003; L. W. Jones et al., 2007). According to the physical activity compendium, activities of daily living such as sweeping a garage or sidewalk of a house would require a MET of approximately 4 METs (Lucia et al., 2003). "
    [Show abstract] [Hide abstract]
    ABSTRACT: This study compared VO(2peak), treatment frequency and dosage, and QOL between 22 post-treated breast cancer survivors (CATotal) and 22 apparently healthy, age-matched women (CO). The CATotal group included 11 with no history of any other co-morbidities (CA) and 11 with controlled hypertension (CA + H). VO(2peak) was measured using the Bruce Protocol. QOL was measured using the SF-36 survey. Significant differences were observed in VO(2peak) between CATotal and CO (p = 0.014), CA and CA + H (p = 0.001), and CA + H and CO (p = 0.001). Physical, emotional, and mental health domains of the SF-36 were significantly different between CATotal and CO (p = 0.006, 0.001, and 0.05 respectively). These results suggest that breast cancer survivors with controlled hypertension can experience a significant reduction in VO(2peak) when compared to apparently healthy, age-matched controls. Also, treatment frequency and dosage affected QOL in this group of survivors.
    Journal of Psychosocial Oncology 07/2010; 28(4):381-98. DOI:10.1080/07347332.2010.484831 · 1.04 Impact Factor
  • Source
    • "Regardless, improved health behaviors can positively impact other. health conditions and quality of life (Herrero et al., 2006). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Little is known about the therapeutic processes contributing to efficacy of psychological interventions for patients with cancer. Data from a randomized clinical trial yielding robust biobehavioral and health effects (B. L. Andersen et al., 2004, 2007) were used to examine associations between process variables, treatment utilization, and outcomes. Novel findings emerged. Patients were highly satisfied with the treatment, but their higher levels of felt support (group cohesion) covaried with lower distress and fewer symptoms. Also, specific treatment strategies were associated with specific outcomes, including lower distress, improved dietary habits, reduced symptomatology, and higher chemotherapy dose intensity. These data provide a comprehensive test of multiple therapeutic processes and mechanisms for biobehavioral change with an intervention including both intensive and maintenance phases.
    Journal of Consulting and Clinical Psychology 01/2008; 75(6):927-38. DOI:10.1037/0022-006X.75.6.927 · 4.85 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The promotion of physical fitness provides individuals direct physiological and psychological benefits that will serve to enhance preventive health. These benefits include: reduction of mortality rates, reduction of blood glucose, improved quality of life in patients with chronic lung diseases, reduced risk of the development of atherosclerosis by increasing high-density lipoproteins, reducing systemic hypertension, reducing body fat, reducing insulin needs, and reducing platelet adhesiveness and aggregation. Physical activity reduces intraocular pressure, increases bone mineral density, and reduces the risk of the development of certain types of cancers. Physical activity reduces the severity of depression and anxiety and stabilizes mood. Individuals who are physically active are less likely to smoke, abuse addictive drugs, abuse alcohol, and are less likely to engage in destructive eating behaviors. This paper also will review the impact of a sedentary lifestyle on society, as well as discuss strategies to increase physical fitness participation.
Show more