Article
Adenoid cystic carcinoma of the buccal vestibule: A case report and review of the literature.
University of Nebraska Medical Center College of Dentistry, 40th and Holdrege Streets, Box 830740, Lincoln, NE 68583-0740, USA.
Oral Oncology (impact factor:
2.86).
12/2006;
42(10):1029-32.
DOI:10.1016/j.oraloncology.2006.06.005
pp.1029-32
Source: PubMed
- Citations (3)
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Cited In (0)
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Article: Analysis of adenoid cystic carcinoma treated by radiotherapy.
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ABSTRACT: The records of 41 patients with adenoid cystic carcinoma of the head and neck region who had been treated with radiotherapy were reviewed. Local control was achieved in 72.3% in the cases with primary lesions at 5 years. The prognosis for tumors that arose in the major salivary glands was better than that for tumors that arose in the minor salivary glands; however, the difference was not statistically significant. In the minor salivary glands, early-stage tumors were well controlled with the use of radiation therapy alone. In spite of the high local control rate, the disease-free survival rate of the patients at 10 years was only 20.8%. Lung metastasis determined the prognosis.Oral Surgery Oral Medicine Oral Pathology 09/1992; 74(2):251-5. -
Article: Tumor-doubling time and onset of pulmonary metastasis from adenoid cystic carcinoma of the salivary gland.
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ABSTRACT: Adenoid cystic carcinoma (ACC), an uncommon malignancy in the head and neck region, invades diffusely and often metastasizes to the lung, although the growth rate is very slow. A retrospective study was conducted in 30 patients with ACC to ascertain the frequency of pulmonary metastasis, the doubling time of metastatic tumor deposits, and the time of onset for pulmonary metastasis. The following results were obtained: (1) Of 30 patients with ACC, 21 had pulmonary metastases (4 initially and 17 during observation), 7 were free of metastases but have not been observed for 5 years, and 2 were free of metastases for more than 5 years but less than 10 years after the initial treatment. The cumulative metastasis rate at 5 and 10 years for this group of patients was 70% and 100%, respectively. (2) Patients with T1 or T2 tumors that have a tubular or cribriform histopathologic pattern showed pulmonary metastases about 20 months later than those with T3 or T4 tumors and a solid pattern. However, the final metastasis rate did not differ between the 2 groups after a long period. (3) The tumor doubling time of the metastatic deposits of ACC was 86 to 1064 days with an average of 393 days, which was much longer than that of most other malignant neoplasms reported previously. (4) The time of onset of pulmonary metastasis was calculated to be much earlier (average of 227 months) before the first visit. These findings suggest that the treatment method for ACC should be chosen with the consideration that many of the patients may have occult pulmonary metastases at the time of their initial evaluation.Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics 11/1999; 88(4):473-8. · 1.46 Impact Factor -
Article: Immunohistochemical expression of CA19-9 and CA125 in mucoepidermoid and adenoid cystic carcinomas of the salivary gland.
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ABSTRACT: This study examined the immunohistochemical expression of carbohydrate antigens CA19-9 and CA125 and their relationship to various biological parameters in 27 mucoepidermoid carcinomas (MEC) and 18 adenoid cystic carcinomas (ACC) arising from salivary glands. The series showed higher immunopositivity for CA125 (67% for MEC; 33% for ACC) than for CA19-9 (59% for MEC; 11% for ACC). CA19-9 epitope was mainly expressed in cystic (MEC) and cribriform/tubular (ACC) components of carcinoma tissues. Solid components in MEC occasionally showed positive staining for CA19-9. CA125 was evenly expressed in both ACC and MEC tissues regardless of their different histological components. The positive expression of CA19-9 and CA125 in the carcinoma tissues did not influence the clinical course of patients with MEC and ACC. A significant relationship was only demonstrated between the immunohistochemical expression of CA125 and the low proliferative activity (LI) evaluated by Ki-67 immunohistochemistry. However, no significant relationship was found between LI and the patients' clinical course. These results suggest that the immunostaining for CA19-9 and CA125 provide no reliable data to predict the clinical course of patients with MEC and ACC of the salivary glands.Oral Oncology 05/2002; 38(3):244-50. · 2.86 Impact Factor
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Keywords
59-year-old Caucasian female patient
acinic cell adenocarcinoma
adenocarcinoma
Adenoid cystic carcinoma
adenoid cystic carcinomas
common intraoral site
common salivary gland malignancy
Greater
Minor salivary gland tumors
mucoepidermoid carcinoma
NOS
polymorphous low-grade adenocarcinoma
protracted clinical course
submandibular glands
