Menopause and determinants of quality of life in women at midlife and beyond: the study of health in pomerania (SHIP).

Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Clinical Research Center of Women's Health, Berlin, Germany.
Menopause (Impact Factor: 3.16). 12/2006; 14(1):123-34. DOI: 10.1097/01.gme.0000227860.58097.e9
Source: PubMed

ABSTRACT Determinants of quality of life (QoL) in pre- and postmenopausal women including nonhormonal modulators of QoL in adult women are not well understood; there is an ongoing controversy about the impact of menopause on health-related QoL. We investigated the extent to which diverse mental and physical symptoms are associated with (a) menopausal status; (b) sociodemographic, psychosocial, and lifestyle factors; and (c) menopausal hormone therapy (MHT) in adult women after the German reunification in a region of the former German Democratic Republic.
The Study of Health in Pomerania is a cross-sectional, population-based survey. Computer-based structured interviews and self-administered questionnaires were used to capture QoL (Zerssen Symptom List) and sociodemographic parameters, psychosocial, and lifestyle indicators (age, socioeconomic status, abuse, social support, nutrition, body mass index, self-rated health, chronic diseases, and use of MHT) in 1,119 pre- and postmenopausal women with an intact uterus.
Analyses suggest that menopausal status was not associated with QoL. MHT was associated with physical, mental, and gastrointestinal symptoms. Age was a significant predictor for cardiopulmonary symptoms and sensory impairment. The relationship between age and both physical and mental complaints was inverse as was the relationship between age and both mood and gastrointestinal symptoms. Age, socioeconomic status, physical and sexual abuse, perceived social support, nutrition, body mass index, self-rated health, chronic diseases, and MHT modulated QoL.
Our findings do not support the hypothesis that QoL is reduced after menopause. Differences between pre- and postmenopausal women can be explained by sociodemographic, psychosocial, and lifestyle factors.

  • Gynakologe. 01/2010; 43(4):282-286.
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    ABSTRACT: Background: Menopause is the time in women’s life when her ovaries stops producing Estrogen and Progesterone, the deficiency of these hormones elicit various somatic, psychological, vasomotor and sexual symptoms that affect the overall quality of life of women. Assessment of quality of life during menopause deserves special attention as with increase in the life expectancy women lives about one third of their lives with hormone deficient state. Studies on menopause and quality of life of menopausal women are scarce and none is conducted before among rural women of Sindh Province, Pakistan. Objective: To investigate the severity of menopausal symptoms associated with menopausal status and to determine the quality of life of menopausal women from rural Sindh. Material and Methods: This cross-sectional survey was conducted in 19 Union Councils of Matiary district, Hyderabad Division from November 2007 to October 2008. Among 5, 25,082 population dwelling in 1509 villages and 56,053 households of these Union Councils, 3062 women were selected by multistage random sampling method within the age range of 40-70 years. Along with collection of socio-demographic data the Menopause rating Scale (MRS) and WHO Quality of life Brief (WHO QOL Brief) Questionnaire translated in Sindhi Language were filled for each individual subject. Data was entered and analyzed by SPSS V 15. Results: The mean age at Menopause was 49.38±14.29 years; the mean scores of menopause rating Scale were high in all domains, the significant difference was found in the mean somatic scores of women in Premenopause, perimenopause and post menopause status (P=<0.001). The psychological symptoms were more severe for women in perimenopause and post menopause status while the scores for urogenital symptoms were found to be higher in perimenopause women (P=<0.001). The mean scores for the physical, psychological, social and environmental domains of WHO QOL questionnaire were found significantly impaired for all women at different status of menopause. Conclusion: To best of our knowledge this is the first attempt to provide data on menopause and quality of life of women from rural Sindh. The mean scores of all the domains of Menopause rating scale were significantly high in Peri and postmenopausal women from rural Sindh. The severity of menopausal symptoms decreases the quality of life in everyday life of these rural women.
    International Journal of Collaborative Research on Internal Medicine & Public Health. 01/2010;
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    ABSTRACT: Our purpose for this study was to identify clusters of midlife women by menopausal symptoms in a multiethnic sample, and to determine ethnic differences in the clusters. This was a secondary analysis of data from 501 women in a larger Internet study on menopausal symptom experiences. The data were analyzed using factor analysis, hierarchical cluster analysis, and multinominal logistic analysis. A three cluster solution was adopted (F = 575.71, p < .01). The clusters differed significantly in the country of birth and ethnicity (p < .05). Only in the low symptomatic cluster were there significant ethnic differences in menopausal symptoms.
    Health Care For Women International 07/2013; · 0.63 Impact Factor


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