Article

Chapter 13: A Comparative Review of CISNET Breast Models Used To Analyze U.S. Breast Cancer Incidence and Mortality Trends

MS, Cornerstone Systems Northwest Inc, Lynden, WA 98264, USA.
JNCI Monographs 02/2006; DOI: 10.1093/jncimonographs/lgj013
Source: PubMed

ABSTRACT The CISNET Breast Cancer program is a National Cancer Institute-sponsored collaboration composed of seven research groups that have modeled the impact of screening and adjuvant treatment on trends in breast cancer incidence and mortality over the period 1975-2000 (base case). This collaboration created a unique opportunity to make direct comparison of results from different models of population-based cancer screening produced in response to the same question. Comparing results in all but the most cursory way necessitates comparison of the models themselves. Previous chapters have discussed the models individual in detail. This chapter will aid the reader in understanding key areas of difference between the models. A focused analysis of differences and similarities between the models is presented with special attention paid to areas deemed most likely to contribute substantially to the results of the target analysis.

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    • "By taking these characteristics into account, it is possible to examine a likely range of outcomes, including extent of illness, mortality and associated costs. Over the past decade, the NCI CISNET program has supported the development of models to examine how changes in screening and treatment have influenced breast cancer mortality (Boer et al. 2004; Clarke et al. 2006; Mandelblatt et al. 2003, 2009; Tosteson et al. 2008). We will adapt the CISNET Spectrum model to examine net improvements in breast cancer outcomes associated with improvement of adherence to screening guidelines and levels of intervention performance achieved by our project. "
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