Amoebiasis: New Understanding and New Goals.

Research and Advanced Studies (Cinvestav), Mexico City, 07360 Mexico.
Parasitology Today (Impact Factor: 5.51). 02/1998; 14(1):1-3. DOI: 10.1016/S0169-4758(97)01176-9
Source: PubMed

ABSTRACT Mexico City, Mexico January 1997.

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Amebiasis is the infection of the human gastrointestinal tract by Entamoeba histolytica, a protozoan parasite that is capable of invading the intestinal mucosa and may spread to other organs, mainly the liver. The detection of Entamoeba histolytica from the nonpathogenic but identically appearing parasites Entamoeba dispar and Entamoeba moshkovskii is an important goal of the clinical microbiology laboratory. Currently, there is no low-cost laboratory test available for the differentiation of E. histolytica from E. dispar infections. It is likely that at least 90% of the infections previously ascribed to E. histolytica are actually E. dispar, while only the remaining 10% are infected with E. histolytica in its new sense. The present manuscript review recent advances in this regard. The purpose of this study is to alert physicians (and perhaps with their help, laboratories) to the importance of distinguishing between the two species of amoebae.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis. Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study. Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically. Serum malondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls (P<0.001). These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients. Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.
    Asian Pacific Journal of Tropical Biomedicine 12/2011; 1(6):478-81.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Entamoeba histolytica is the etiological agent of invasive amoebiasis, the third leading parasitic cause of mortality in the world. Our aim was to find a molecular correlation between a glucosephosphate isomerase zymodeme analyses in E. histo-lytica zymodemes. It was demonstrated that natural and recombinant glucosephosphate isomerase enzymes of E. histolytica comigrated in the starch gel electrophoresis, indicating that the isoenzyme pattern of E. histolytica glucosephosphate isom-erase could be explained from the primary sequences alone and means that expression of the polypeptides of the described sequences in Escherichia coli are able to reproduce the classical glucosephosphate isomerase isoenzyme patterns.
    Iranian J Publ Health. 01/2005; 34(4):35-40.