Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects

Abteilung für Evolutionsgenetik, Institut für Genetik, Universität zu Köln, Köln 50674, Germany.
Genome Research (Impact Factor: 14.63). 12/2006; 16(11):1334-8. DOI: 10.1101/gr.5204306
Source: PubMed


Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups of holometabolous insects so far. Here, we utilize emerging genome projects to assemble and analyze a data set of 185 nuclear genes, resulting in a fully resolved phylogeny of the major insect model species. Contrary to the most widely accepted phylogenetic hypothesis, bees and wasps (Hymenoptera) are basal to the other major holometabolous orders, beetles (Coleoptera), moths (Lepidoptera), and flies (Diptera). We validate our results by meticulous examination of potential confounding factors. Phylogenomic approaches are thus able to resolve long-standing questions about the phylogeny of insects.

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    • "optera ) . The results of this phylogenomics study suggested that bees and wasps occupy the basal position in the phylogeny of the holometabolous insects . Later , a maximum - likelihood tree generated from concatenated sequences of 1150 single - copy orthologues amongst 10 metazoan species ( Richards et al . , 2008 ) also confirmed the results of Savard et al . ( 2006 ) . A recent phylogenom - ics study ( Peters et al . , 2014 ) exploited de novo transcrip - tome data to study holometabolous insects ."
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    Insect Molecular Biology 05/2015; 24(4). DOI:10.1111/imb.12174 · 2.59 Impact Factor
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    • "Thus, we conclude that each of the four independent transitions to holocentricity in insects was associated with CenH3 loss. Phylogenetic analyses of CenH3 and other H3 proteins based on their homologous histonefold domains reveal a topology of insect CenH3s that is largely consistent with the expected branching order of the insect species (Whiting, 2002; Grimaldi and Engel, 2005; Savard et al., 2006) (Figure 1— figure supplement 6), confirming that the absence of CenH3 in holocentric insects is due to recurrent loss rather than reinvention or horizontal transfer of CenH3 in monocentric insect lineages. "
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