Cerebrovascular disease basis of depression: post-stroke depression and vascular depression.

Department of Psychiatry, The Johns Hopkins Hospital, Baltimore, USA.
International Review of Psychiatry (Impact Factor: 1.8). 11/2006; 18(5):433-41. DOI: 10.1080/09540260600935447
Source: PubMed

ABSTRACT The close association between cerebrovascular disease and depression has been known for more than a century, yet much of the progress in understanding the cerebrovascular basis of depression in late life has been spurred by development of two concepts: 'post-stroke depression' and 'vascular depression'. The purpose of this review is to examine the epidemiology, diagnostic features, course, pathophysiology and prognosis of post-stroke depression and vascular depression, to highlight their common features, and to contrast the distinct aspects of these two subtypes of geriatric depression.

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