Article

Mycoplasma qenitalium: Prevalence and behavioural risk factors in the general population

Research Unit for General Practice, Vennelyst Boulevard 6, DK-8000 Aarhus C, Denmark.
Sexually Transmitted Infections (Impact Factor: 3.08). 07/2007; 83(3):237-41. DOI: 10.1136/sti.2006.022970
Source: PubMed

ABSTRACT Mycoplasma genitalium has been shown to cause urethritis in men and cervicitis in women and may also be a causative agent in female infertility.
To estimate the prevalence of urogenital M genitalium infection and identify sexual behavioural risk factors in the general population.
Participating individuals were 731 men and 921 women aged 21-23 years and not seeking the healthcare system because of symptoms. They answered questionnaires on sexual behaviour and provided samples for M genitalium testing.
In women aged 21-23 years, the prevalence of infection was 2.3% (21/921) and in men of the same age it was 1.1% (8/731). For both sexes, an increasing number of partners was associated with a greater chance of being infected. Among women a shorter duration of a steady relationship and having a partner with symptoms was associated with being infected, and for men younger age at first intercourse was associated with M genitalium infection.
We conclude that the prevalence of infection in the general population is too low for population-based screening. However, the development of test algorithms based on behavioural risk factors is a promising alternative.

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Available from: Berit Andersen, Jul 29, 2015
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    • "Many studies confirm low percentage of M. genitalium in healthy women without symptoms: 4.5% of positive cases were described by English authors [24]. In Denmark, among 731 men and 921 women aged 21–23 without any symptoms in the urogenital tract, M. genitalium DNA was demonstrated in 2.3% women and in 1.1% men [25]. M. genitalium is clearly defined as an etiologic agent of STI. "
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    • "In 2009, for this subsequent study, previously collected urine samples stored at −70 • C were tested for M. genitalium and C. trachomatis. M. genitalium PCR testing has been conducted in other studies stored frozen specimens for up to eight years [19] [27] [28]. Of the 285 samples sent for analysis, 216 samples (82 cases and 134 controls) were sufficient for analysis. "
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