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Griel AE, Kris-Etherton PM. Tree nuts and the lipid profile: a review of clinical studies. Br J Nutr 96(Suppl 2), S68-S78

Pennsylvania State University, S-126 Henderson Building, University Park, PA 16802, USA.
British Journal Of Nutrition (Impact Factor: 3.34). 12/2006; 96 Suppl 2(Suppl 2):S68-78. DOI: 10.1017/BJN20061866
Source: PubMed

ABSTRACT Tree nuts have a fatty acid profile that favourably affects blood lipids and lipoproteins. They are low in saturated fat and high in unsaturated fatty acids and are rich sources of other nutrients. An extensive database consistently shows total and LDL cholesterol-lowering effects of diets low in saturated fat and cholesterol and high in unsaturated fat provided by a variety of tree nuts. Collectively, a summary of studies conducted to date shows that tree nuts reduce LDL cholesterol by 3-19 % compared with Western and lower-fat diets. Nuts also contain many nutrients and bioactive compounds that appear to contribute to the favourable effects on lipids and lipoproteins--these include plant sterols, dietary fibre and antioxidants. Because of their unique nutrient profile, nuts can be part of a diet that features multiple heart-healthy foods resulting in a cholesterol lowering response that surpasses that of cholesterol-lowering diets typically used to reduce CVD risk.

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    • "Nut consumption (such as almond) cause improvements in triglycerides, total cholesterol (TC),[9] and low density lipoprotein-cholesterol (LDL-C) and so it has positive effects on various cardiovascular disease risk factors.[91011] Moreover, observational studies show that nut consumption is associated with a lower risk of developing coronary artery disease, hypertension, and type 2 diabetes.[121314] "
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    • "Since this study, more than 25 clinical studies have been conducted to evaluate the effects of nut consumption on serum lipids and lipoproteins. Although the degree of dietary control has been variable, ranging from being tightly controlled to simply providing dietary advice, the results have been consistent in showing a cholesterollowering effect of regular nut consumption [90] [91]. In agreement , Mukuddem-Petersen et al. [42] showed that the consumption of 50 to 100 g of nuts at least five times per week as a part of a heart-healthy diet with a total fat content of 35% in a randomized controlled intervention trial significantly decreased TC and LDL-C. "
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